β-carotene protects rats against bronchitis induced by cigarette smoking
  • 万方数据
    中华医学杂志(英文版) 중화의학잡지(영문판)
    CHINESE MEDICAL JOURNAL
    2003年 4期 514-516 ,共3页

    庞宝森%王辰%翁心植%唐小奈%张红玉%牛淑洁%毛燕玲%辛平%黄秀霞%张海燕%祝锦

    방보삼%왕신%옹심식%당소내%장홍옥%우숙길%모연령%신평%황수하%장해연%축금



    smoke%bronchitis%β-carotene


    Objective To investigate the protective effects of β-carotene in rats against the development of chronic bronchitis induced by cigarette smoking. Results Long-term cigarette smoking caused an obvious increase in the amount of IL-6, IL-8 and LPO and a sharp decrease in the levels of NO and SOD in smoking animals compared to controls. β-carotene intake reversed all the changes induced by smoking and alleviated the pathological changes caused by chronic bronchitis. Conclusions Quantitative oral intake of β-carotene had protective effects against chronic bronchitis induced by long-term cigarette smoking, which was associated with the increased production of NO, the clearance of some oxidative free radicals (OFR) and the alleviation of chronic inflammation.
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