第三军医大学学报
第三軍醫大學學報
제삼군의대학학보
ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE
2001年
4期
471-472
,共2页
大肠炎性息肉%IgG亚类%T细胞亚群
大腸炎性息肉%IgG亞類%T細胞亞群
대장염성식육%IgG아류%T세포아군
目的 了解大肠炎性息肉病人与免疫功能改变的相关性。方法 经电子(纤维)结肠镜行120例大肠炎性息肉摘除术，对息肉组织进行病理学观察，并对其外周血T细胞亚群和IgG亚类以ELISA及IFA法进行检测。结果 实验组CD8明显低于对照组，CD4/CD8高于对照组（P<0.01）,IgG2和IgG4也明显高于对照组（P<0.01）。结论 大肠炎性息肉的发病原因可能与体液免疫和细胞免疫功能失调有关。
目的 瞭解大腸炎性息肉病人與免疫功能改變的相關性。方法 經電子(纖維)結腸鏡行120例大腸炎性息肉摘除術，對息肉組織進行病理學觀察，併對其外週血T細胞亞群和IgG亞類以ELISA及IFA法進行檢測。結果 實驗組CD8明顯低于對照組，CD4/CD8高于對照組（P<0.01）,IgG2和IgG4也明顯高于對照組（P<0.01）。結論 大腸炎性息肉的髮病原因可能與體液免疫和細胞免疫功能失調有關。
목적 료해대장염성식육병인여면역공능개변적상관성。방법 경전자(섬유)결장경행120례대장염성식육적제술，대식육조직진행병이학관찰，병대기외주혈T세포아군화IgG아류이ELISA급IFA법진행검측。결과 실험조CD8명현저우대조조，CD4/CD8고우대조조（P<0.01）,IgG2화IgG4야명현고우대조조（P<0.01）。결론 대장염성식육적발병원인가능여체액면역화세포면역공능실조유관。
Objective To study the corelation between patient with inflammatory polyp of large intestine and the changes of immunologic function. Methods Polyps of large intestine were extirpated from 120 patients with fiberoptic colonoscope and the pathological changes were studies. IgG subclass and T cell subsets in the peripheral blood were determined by ELISA and IFA methods. Similar parameters were determined in 30 cases of chronic colitis as control. Results CD8 in patients were lower than that of the control and CD4/CD8 were increased compared with those in control. Conclusion Disorder of humoral and cellular immunity might play an important role on the pathogenesis of polyp of large intestine.
