江汉大学学报：自然科学版
江漢大學學報：自然科學版
강한대학학보：자연과학판
Journal of Jianghan University:Natural Sciences
2011年
3期
75-78
,共4页
针药结合%糖尿病周围神经病变(DPN)%空腹血糖(FBG)%餐后血糖(PBG)%NO%SOD%MDNS评分
針藥結閤%糖尿病週圍神經病變(DPN)%空腹血糖(FBG)%餐後血糖(PBG)%NO%SOD%MDNS評分
침약결합%당뇨병주위신경병변(DPN)%공복혈당(FBG)%찬후혈당(PBG)%NO%SOD%MDNS평분
acupuncture combined medicine treatment%diabetic peripheral neuropathies（DPN）%FBG%PBG%NO%SOD%MDNS
目的：观察和比较针药结合对糖尿病周围神经病变（DPN）患者FBG、PBG、NO和SOD含量和MDNS评分的影响,探讨针药结合的作用机制.方法：将70例患者随机分为两组比较观察,有完整资料者58例,其中针药治疗组33例,药物对照组25例.结果：治疗3周后,治疗组和对照组都能使空腹血糖（FBG）及餐后血糖（PBG）显著下降,治疗组餐后血糖比对照组下降更为明显,P〈0.05,而空腹血糖的下降两组间无明显差异;两组的NO含量和药物组SOD的含量无明显影响（P〉0.05）;而针药组的SOD值升高和MDNS改善明显优于对照组,P〈0.05;MDNS评分与FBG、PBG明显正相关,与NO和SOD含量呈负相关.结论：针药结合能对单纯药物治疗控制较差的餐后血糖起明显调节作用;针药结合能有效提高SOD水平,改善糖尿病周围神经病变患者MDNS评分,提高临床疗效;但短期疗效上,针药结合对NO含量无明显影响.
目的：觀察和比較針藥結閤對糖尿病週圍神經病變（DPN）患者FBG、PBG、NO和SOD含量和MDNS評分的影響,探討針藥結閤的作用機製.方法：將70例患者隨機分為兩組比較觀察,有完整資料者58例,其中針藥治療組33例,藥物對照組25例.結果：治療3週後,治療組和對照組都能使空腹血糖（FBG）及餐後血糖（PBG）顯著下降,治療組餐後血糖比對照組下降更為明顯,P〈0.05,而空腹血糖的下降兩組間無明顯差異;兩組的NO含量和藥物組SOD的含量無明顯影響（P〉0.05）;而針藥組的SOD值升高和MDNS改善明顯優于對照組,P〈0.05;MDNS評分與FBG、PBG明顯正相關,與NO和SOD含量呈負相關.結論：針藥結閤能對單純藥物治療控製較差的餐後血糖起明顯調節作用;針藥結閤能有效提高SOD水平,改善糖尿病週圍神經病變患者MDNS評分,提高臨床療效;但短期療效上,針藥結閤對NO含量無明顯影響.
목적：관찰화비교침약결합대당뇨병주위신경병변（DPN）환자FBG、PBG、NO화SOD함량화MDNS평분적영향,탐토침약결합적작용궤제.방법：장70례환자수궤분위량조비교관찰,유완정자료자58례,기중침약치료조33례,약물대조조25례.결과：치료3주후,치료조화대조조도능사공복혈당（FBG）급찬후혈당（PBG）현저하강,치료조찬후혈당비대조조하강경위명현,P〈0.05,이공복혈당적하강량조간무명현차이;량조적NO함량화약물조SOD적함량무명현영향（P〉0.05）;이침약조적SOD치승고화MDNS개선명현우우대조조,P〈0.05;MDNS평분여FBG、PBG명현정상관,여NO화SOD함량정부상관.결론：침약결합능대단순약물치료공제교차적찬후혈당기명현조절작용;침약결합능유효제고SOD수평,개선당뇨병주위신경병변환자MDNS평분,제고림상료효;단단기료효상,침약결합대NO함량무명현영향.
Objective：To observe and compare the influences on FBG,PBG,NO,SOD and MDNS on the patients of diabetic peripheral neuropathies（DPN）by acupuncture combined with medicine.Methods：70 patients were randomly divided into 2 groups.And there were 58 patients with comprehensive datas among which the acupuncture combined with medicine group included 33 cases and the medicine comparison group included 25 cases.Results：After 3 weeks＇ treatment,both groups can obviously decrease FBG and PBG.acupuncture combined with medicine group could obviously decrease PBG,compared with the controlled group,acupuncture combined with medicine group decreased the contest of PBG much better﹙ P0.05﹚.There were no differences between the two groups in FBG.Both groups＇ NO and the medicine comparison group＇s SOD had no obvious differences P0.05.The acupuncture combined with medicine group＇s SOD increased and MDNS changed more obviously than medicine comparison group﹙ P0.05﹚.The contents of NO and SOD are negatively correlated with the MDNS,while FBG and PBG are positively correlated.Conclusion：Acupuncture combined with medicine can control the PBG appropriately better than the controlled group,can improve the contents of SOD and can improve the MDNS better in DPN patients,so improve clinical treatment effect.But there is no obvious influence on the contents of NO in the acupuncture combined with medicine group after the short-term therapy.
