中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2012年
6期
524-526
,共3页
庞良俊%尹良爽%朱春燕%汪咏梅%董文文%戴兢%杨琪%孙刚强%黄豹
龐良俊%尹良爽%硃春燕%汪詠梅%董文文%戴兢%楊琪%孫剛彊%黃豹
방량준%윤량상%주춘연%왕영매%동문문%대긍%양기%손강강%황표
酒依赖%注意偏向%Stroop任务
酒依賴%註意偏嚮%Stroop任務
주의뢰%주의편향%Stroop임무
Alcohol dependent%Attentional bias%Stroop task
目的 探讨戒酒初期男性酒依赖患者( alcohol dependence,AD)注意偏向特点及与相关因素.方法 选取30例戒酒初期的男性AD患者以及与其人口学资料相匹配的37例健康对照组(HC)作为研究对象,采用中文情绪词stroop实验进行注意偏向的测试.结果 AD组在中性词、负性词、线索词的反应时[分别为(1382.13±323.38)ms,( 1365.76±313.03) ms,(1433.20±342.23)ms],高于HC组[分别为(797.27±216.97)ms,(794.11±209.41 )ms,(799.40±215.82)ms],差异有统计学意义(t=8.827,P＜0.001；t=8.922,P＜0.01；t =9.234,P＜0.01)；AD组对中性词、负性词的错误数[(3.70±2.56)次,(4.23±2.53)次],高于HC组[(2.11±1.87)次,(1.92±1.82)次],差异有统计学意义(t=2.939,P=0.005；t=4.355,P＜0.01)；在线索词错误数方面差异无统计学意义；酒相关线索词的注意偏向与首次饮酒年龄存呈负相关(P＜0.05),与持续饮酒时间及抑郁自评量表得分呈正相关(P＜0.05)；成瘾年龄和焦虑自评量表总分进入回归方程.结论 戒酒初期男性AD患者对酒相关线索具有显著的注意偏向,这可能与犒赏中枢的异常激活有关.
目的 探討戒酒初期男性酒依賴患者( alcohol dependence,AD)註意偏嚮特點及與相關因素.方法 選取30例戒酒初期的男性AD患者以及與其人口學資料相匹配的37例健康對照組(HC)作為研究對象,採用中文情緒詞stroop實驗進行註意偏嚮的測試.結果 AD組在中性詞、負性詞、線索詞的反應時[分彆為(1382.13±323.38)ms,( 1365.76±313.03) ms,(1433.20±342.23)ms],高于HC組[分彆為(797.27±216.97)ms,(794.11±209.41 )ms,(799.40±215.82)ms],差異有統計學意義(t=8.827,P＜0.001；t=8.922,P＜0.01；t =9.234,P＜0.01)；AD組對中性詞、負性詞的錯誤數[(3.70±2.56)次,(4.23±2.53)次],高于HC組[(2.11±1.87)次,(1.92±1.82)次],差異有統計學意義(t=2.939,P=0.005；t=4.355,P＜0.01)；在線索詞錯誤數方麵差異無統計學意義；酒相關線索詞的註意偏嚮與首次飲酒年齡存呈負相關(P＜0.05),與持續飲酒時間及抑鬱自評量錶得分呈正相關(P＜0.05)；成癮年齡和焦慮自評量錶總分進入迴歸方程.結論 戒酒初期男性AD患者對酒相關線索具有顯著的註意偏嚮,這可能與犒賞中樞的異常激活有關.
목적 탐토계주초기남성주의뢰환자( alcohol dependence,AD)주의편향특점급여상관인소.방법 선취30례계주초기적남성AD환자이급여기인구학자료상필배적37례건강대조조(HC)작위연구대상,채용중문정서사stroop실험진행주의편향적측시.결과 AD조재중성사、부성사、선색사적반응시[분별위(1382.13±323.38)ms,( 1365.76±313.03) ms,(1433.20±342.23)ms],고우HC조[분별위(797.27±216.97)ms,(794.11±209.41 )ms,(799.40±215.82)ms],차이유통계학의의(t=8.827,P＜0.001；t=8.922,P＜0.01；t =9.234,P＜0.01)；AD조대중성사、부성사적착오수[(3.70±2.56)차,(4.23±2.53)차],고우HC조[(2.11±1.87)차,(1.92±1.82)차],차이유통계학의의(t=2.939,P=0.005；t=4.355,P＜0.01)；재선색사착오수방면차이무통계학의의；주상관선색사적주의편향여수차음주년령존정부상관(P＜0.05),여지속음주시간급억욱자평량표득분정정상관(P＜0.05)；성은년령화초필자평량표총분진입회귀방정.결론 계주초기남성AD환자대주상관선색구유현저적주의편향,저가능여호상중추적이상격활유관.
Objective To explore the attentional biases in male alcohol dependent (AD) patients and the correlations between the attentional bias and alcohol-related factors.Methods A total of 30 recently detoxified male individuals with alcoholism were compared with 37 healthy controls ( HC ) on the Chinese Emotional Stroop Task using negative,neutral,and alcohol-related words.Results The comparison between AD group( ( 1382.13 ±323.38) ms,( 1365.76 ±313.03)ms,( 1433.20 ±342.23) ms,respectively) and HC group( (797.27 ±216.97)ms,( 794.11 ± 209.41 ) ms,(799.40 ± 215.82 ) ms respectively) on the reaction time of neutral,negative and alcohol-related words were significant ( t =8.822,P ＜ 0.001 ; t =8.922,P ＜ 0.001 ; t =9.234,P ＜ 0.001 ).The error number of of the neutral and negative- related words of the patients ( ( 3.70 ± 2.56) time,( 4.23 ± 2.53 ) time)was worse than that of HC group( ( 2.11 ± 1.87 ) time,( 1.92 ± 1.82 ) time) ( t =2.939,P =0.005 ; t =4.355,P ＜0.01 ).Error number of the alcohol- related words between two groups were not significant;Its alcohol-related words attentional bias negative correlation to the age of initial alcohol use(P＜ 0.05 ),and positive correlation to continue drinking and score of self-rating depression scale (P＜0.05).Age of addiction and the score of self-rating anxiety scale enter the regression equation of alcohol-related words.Conclusion These results demonstrate that alcoholics have attentional bias in alcohol-related words and reward-related brain regions may be associated with craving among male patients with attentional bias.
