CAJ | 학술논문

目的研究摩擦刺激足三里等下肢穴位对小脑的激活与去激活效应.方法共10例健康右利手受试者接受功能性磁共振成像(fMRI)研究,采用3.0 T Siemens Magnetom Trio磁共振成像系统采集全脑功能像.穴位选取右侧足三里、阴陵泉、丰隆和三阴交穴,刺激采用组块设计模式,刺激期操作者使用海绵用力摩擦受试者穴位区,频率约为2 Hz.以SPM5和SUIT软件包分析数据,识别相对于基线水平,刺激不同穴位在小脑引发的激活和去激活效应信号,并计算小脑28个分区中激活和去激活信号的均值.结果不同穴位对于小脑半球各分区的影响方式均不相同,但各穴位激活效应均值最大值所在分区均为小脑蚓部CrusⅠ区;除三阴交外,各穴位的去激活效应最大值所在分区均为小脑蚓部Ⅵ区.在小脑半球20个分区中,各穴位刺激引起的左右两侧激活效应的变化趋势基本一致,但多数区域右侧的均值高于左侧.结论刺激足三里等下肢穴位对小脑的调节效应既存在共性,也存在特异性.这一结果有助于针刺治疗中穴位的选择.
목적 연구마찰자격족삼리등하지혈위대소뇌적격활여거격활효응.방법 공10례건강우리수수시자접수공능성자공진성상(fMRI)연구,채용3.0 T Siemens Magnetom Trio자공진성상계통채집전뇌공능상.혈위선취우측족삼리、음릉천、봉륭화삼음교혈,자격채용조괴설계모식,자격기조작자사용해면용력마찰수시자혈위구,빈솔약위2 Hz.이SPM5화SUIT연건포분석수거,식별상대우기선수평,자격불동혈위재소뇌인발적격활화거격활효응신호,병계산소뇌28개분구중격활화거격활신호적균치.결과 불동혈위대우소뇌반구각분구적영향방식균불상동,단각혈위격활효응균치최대치소재분구균위소뇌인부CrusⅠ구;제삼음교외,각혈위적거격활효응최대치소재분구균위소뇌인부Ⅵ구.재소뇌반구20개분구중,각혈위자격인기적좌우량측격활효응적변화추세기본일치,단다수구역우측적균치고우좌측.결론 자격족삼리등하지혈위대소뇌적조절효응기존재공성,야존재특이성.저일결과유조우침자치료중혈위적선택.
Objective To investigate any effects of rubbing acupoints on the right leg on activation and deactivation responses in the human cerebellum. Methods Ten male, healthy, right-handed subjects were examined using functional magnetic resonance imaging (fMRI) while their Zusanli (ST36) , Yanglingquan (GB34),Fenglong (ST40) and Sanyinjiao (SP6) acupoints on the right lower extremity were stimulated. A block-designed method was applied. A piece of sponge was used to rub all the above-mentioned acupoints for stimulation. The mean values of the activation and deactivation signals in different cerebellar zones induced by stimulating each acupoint were calculated.Results Each acupoint could modulate cerebellum function in its specific way, but all acupoints induced the largest mean values in the Vermis Crus I area. The largest deactivation effects for all acupoints except Sanyinjiao were located in the Vermis VI area. For each acupoint, left and right side activation effects of the 20 zones of the cerebellum were basically consistent, though the mean values of most zones were higher on the right side. Conclusions The four acupoints studied not only shared common modulating effects, but also showed point-specific influence on cerebellum function. The effects exerted by each acupoint on the Vermis were greater than that on the cerebellar hemispheres. The phenomena observed in this study could contribute to acupoint selection during rehabilitation.