CAJ | 학술논문

目的观察低频重复经颅磁刺激(rTMS)对脑梗死后失语患者语言功能的康复疗效.方法选取28例脑梗死后运动性失语恢复期的患者作为研究对象,按随机数字表法分为磁刺激组和对照组,每组14例,均进行常规药物治疗及语言康复训练.磁刺激组用低频rTMS进行语言康复治疗刺激,而对照组则用低频rTMS行假刺激,每天10个序列,共10 d.采用中国康复研究中心失语症检查法(CRRCAE)分析比较2组患者低频rTMS治疗前、治疗结束时及治疗后90 d的评分.结果与治疗前及对照组比较,磁刺激组在低频rTMS治疗结束时的CRRCAE评分差异均有统计学意义(P＜0.05).与治疗前及治疗刚结束时比较,磁刺激组在治疗后90 d时的CRRCAE评分差异均有统计学意义(P＜0.01)；与对照组比较,磁刺激治疗后90 d时磁刺激组的CRRCAE评分差异也有统计学意义(P＜0.05).在低频rTMS治疗后90 d时,磁刺激组CRRCAE评分中“说”项评分与治疗前及对照组比较,差异均有统计学意义(P＜0.05).结论低频rTMS不仅可短期改善脑梗死后运动性失语恢复期的语言功能,而且可起到持久的语言康复治疗作用；低频rTMS可能对脑梗死后运动性失语恢复期患者的说话功能具有较好的康复治疗作用.
목적 관찰저빈중복경로자자격(rTMS)대뇌경사후실어환자어언공능적강복료효.방법 선취28례뇌경사후운동성실어회복기적환자작위연구대상,안수궤수자표법분위자자격조화대조조,매조14례,균진행상규약물치료급어언강복훈련.자자격조용저빈rTMS진행어언강복치료자격,이대조조칙용저빈rTMS행가자격,매천10개서렬,공10 d.채용중국강복연구중심실어증검사법(CRRCAE)분석비교2조환자저빈rTMS치료전、치료결속시급치료후90 d적평분.결과 여치료전급대조조비교,자자격조재저빈rTMS치료결속시적CRRCAE평분차이균유통계학의의(P＜0.05).여치료전급치료강결속시비교,자자격조재치료후90 d시적CRRCAE평분차이균유통계학의의(P＜0.01)；여대조조비교,자자격치료후90 d시자자격조적CRRCAE평분차이야유통계학의의(P＜0.05).재저빈rTMS치료후90 d시,자자격조CRRCAE평분중“설”항평분여치료전급대조조비교,차이균유통계학의의(P＜0.05).결론 저빈rTMS불부가단기개선뇌경사후운동성실어회복기적어언공능,이차가기도지구적어언강복치료작용；저빈rTMS가능대뇌경사후운동성실어회복기환자적설화공능구유교호적강복치료작용.
Objective To investigate the rehabilitative effect of low frequency repetitive transcranial magnetic stimulation (rTMS) on convalescing patients with Broca's aphasia. Methods Twenty-eight patients with Broca's aphasia recovering from cerebral infarction were randomly divided into a stimulation group and a control group with 14 subjects in each.Patients in the control group accepted conventional drugs,speech rehabilitation and sham stimulation,while patients in the stimulation group were in given low frequency rTMS in place of the sham stimulation.Their speech performance was evaluated using the China Rehabilitation Research Center's aphasia examination (CRRCAE) pre-stimulation,post-stimulation and 90 days later. Results Compared with before treatment and with the controls,the speaking scores of the stimulation group increased significantly after treatment and also 90 days later. Conclusion Low frequency rTMS can not only improve the speech performance of Broca's aphasia sufferers in the short term,but it also plays a lasting role.It may thus have clinical application for patients with Broca's aphasia.