中国牛业科学
中國牛業科學
중국우업과학
CHINA CATTLE SCIENCE
2012年
1期
33-37
,共5页
赵静%张春雷%房兴堂%陈宏
趙靜%張春雷%房興堂%陳宏
조정%장춘뢰%방흥당%진굉
WNT信号%β-catenin%脂肪细胞%通路
WNT信號%β-catenin%脂肪細胞%通路
WNT신호%β-catenin%지방세포%통로
Wnt signaling pathway%β-catenin%adipose cell
Wnt(wingless-type MMTV integration site family members)信号通路与细胞的发育分化密切相关,对正常和肿瘤细胞生长都至关重要,因其启动蛋白为Wnt蛋白而得名。本文综述了Wnt蛋白家族、Wnt信号通路、Wnt信号通路与疾病的关系以及WNT信号通路的研究进展,并对家族中一些成员的研究进行了展望。
Wnt(wingless-type MMTV integration site family members)信號通路與細胞的髮育分化密切相關,對正常和腫瘤細胞生長都至關重要,因其啟動蛋白為Wnt蛋白而得名。本文綜述瞭Wnt蛋白傢族、Wnt信號通路、Wnt信號通路與疾病的關繫以及WNT信號通路的研究進展,併對傢族中一些成員的研究進行瞭展望。
Wnt(wingless-type MMTV integration site family members)신호통로여세포적발육분화밀절상관,대정상화종류세포생장도지관중요,인기계동단백위Wnt단백이득명。본문종술료Wnt단백가족、Wnt신호통로、Wnt신호통로여질병적관계이급WNT신호통로적연구진전,병대가족중일사성원적연구진행료전망。
Wnt(wingless-type MMTV integration site family members) signaling pathway is closely related to cell development and differentiation,which is essential for normal and tumor cell growth.Because its promoting protein is Wnt protein,it named by Wnt protein.In this paper,the Wnt protein family,Wnt signaling pathway,the relationship between Wnt signaling pathway and disease,and research on Wnt signaling pathway are reviewed.At last,researches on some members of the family are prospected.