CAJ | 학술논문

目的探讨肝脏局灶性结节性增生症(FNH)的临床特点与治疗方法.方法回顾性分析15例经病理学检查证实的FNH患者的临床资料.结果 FNH的临床表现多无症状或偶有上腹部隐痛;肝脏影像学表现多为结节性病灶,CT平扫多为等密度或低密度,动脉期明显强化.15例FNH患者,经穿刺活检病理学证实者5例,手术后病理诊断10例;手术切除10例(7例采用不规则性部分肝切除术,1例行肝S7段切除,2例行肝左外叶切除术),行经皮肝穿刺病灶化学消融术2例,观察3例;随访未见复发或进展、恶变等.结论 FNH是一种肝脏良性病变,临床表现无特异性,确诊依赖于病理学检查,治疗以手术切除为主,部分未行手术切除者需密切随访.
목적 탐토간장국조성결절성증생증(FNH)적림상특점여치료방법.방법 회고성분석15례경병이학검사증실적FNH환자적림상자료.결과 FNH적림상표현다무증상혹우유상복부은통;간장영상학표현다위결절성병조,CT평소다위등밀도혹저밀도,동맥기명현강화.15례FNH환자,경천자활검병이학증실자5례,수술후병리진단10례;수술절제10례(7례채용불규칙성부분간절제술,1례행간S7단절제,2례행간좌외협절제술),행경피간천자병조화학소융술2례,관찰3례;수방미견복발혹진전、악변등.결론 FNH시일충간장량성병변,림상표현무특이성,학진의뢰우병이학검사,치료이수술절제위주,부분미행수술절제자수밀절수방.
Objective To study the diagnosis and treatment of hepatic focal nodular hyperplasia(FNH).Methods The clinical data of 15 FNH patients proved by pathological examination were retrospectively analyzedResults Most cases of FNH were asymptomatic,and some had nonspecific symptom such as dull pain of upper abdomen.Most cases of FNH showed nodular lesion on liver imaging with isodensity or hypodensity on pre-contrast CT scan and strong enhancement during arterial phase.of the 15 FNH patients,5 eases were diagnosed by needle biopsy pathology,10 cases were diagnosed by postoperative pathology.And 10 cases underwent surgical resection(7 cages with irregular hepatectomy,1 case with resection of segment 7,2 cases with left lateral lobeetomy),2 cases underwent percutaneous transhepafic chemical ablation,3 cases underwent clinical observation.All cases were followed up,and no recurence or malignancy were found.Conclusion FNH is a kind of benign tumor of liver without specific clinical manifestation.Accurate diagnosis needs pathological examination.Surgical treatment is recommended in most cages.Close follow-up is recommended in cases without operation.