CAJ | 학술논문

目的　比较缓释沙丁胺醇（沙博特）和全特宁在支气管哮喘治疗中的作用。方法　采用随机对照试验方法，使用沙博特和全特宁分别治疗20例哮喘患者2周,观察在治疗前、后肺功能FEV1、FEV1%、PEF，自我症状评分及喘乐宁用量的变化。结果　治疗后肺功能FEV1占预计值%、PEF和自我症状评分均有显著改善（P<0.05），喘乐宁用量明显减少（P<0.05），沙博特和全特宁两组之间无显著差异。结论　沙博特治疗支气管哮喘具有与全特宁相似的疗效及安全性。
목적　비교완석사정알순（사박특）화전특저재지기관효천치료중적작용。방법　채용수궤대조시험방법，사용사박특화전특저분별치료20례효천환자2주,관찰재치료전、후폐공능FEV1、FEV1%、PEF，자아증상평분급천악저용량적변화。결과　치료후폐공능FEV1점예계치%、PEF화자아증상평분균유현저개선（P<0.05），천악저용량명현감소（P<0.05），사박특화전특저량조지간무현저차이。결론　사박특치료지기관효천구유여전특저상사적료효급안전성。
Objective　In a RCT study, the safety and efficacy of sabot (a slow-release salbuteral) and volmax (controlled-release salbuterol) were compared in bronchial asthma. Methods　40 patients with moderate to severe asthma were randomly divided into two groups and treated by sabot or volmax for 2 weeks. The FEV1%, peak expiratory flow (PEF), symptom score and use of rescue ventolin were measured to evaluate the effect of treatment. Results　After treatment FEV1%, PEF and symptom score improved and the need for inhaling short-acting beta 2-agonis in both groups reduced significantly. There was no difference of these improvement between two groups. Conclusion　The safety and efficacy of sabot for treatment of asthma was similar to volmax.