植物学通报
植物學通報
식물학통보
CHINESE BULLETIN OF BOTANY
2001年
1期
3-10
,共8页
真核mRNA%3′-非翻译区%转录后调控
真覈mRNA%3′-非翻譯區%轉錄後調控
진핵mRNA%3′-비번역구%전록후조공
真核生物mRNA的3′非翻译区(3′_UTR)在基因表达的转录后调控中起着重要作用:3′_UTR内存在末端加工信号以指导mRNA3′末端的加工；3′_UTR不但控制mRNA的稳定性及降解速率、协助辨认特殊密码子，而且还控制着mRNA的翻译时间、位点及控制其翻译起始及效率等。
真覈生物mRNA的3′非翻譯區(3′_UTR)在基因錶達的轉錄後調控中起著重要作用:3′_UTR內存在末耑加工信號以指導mRNA3′末耑的加工；3′_UTR不但控製mRNA的穩定性及降解速率、協助辨認特殊密碼子，而且還控製著mRNA的翻譯時間、位點及控製其翻譯起始及效率等。
진핵생물mRNA적3′비번역구(3′_UTR)재기인표체적전록후조공중기착중요작용:3′_UTR내존재말단가공신호이지도mRNA3′말단적가공；3′_UTR불단공제mRNA적은정성급강해속솔、협조변인특수밀마자，이차환공제착mRNA적번역시간、위점급공제기번역기시급효솔등。
The 3′ untranslated region (3′-UTR) of eukaryotic transcripts plays an important role in regulating gene expression on post-transcriptional level. 3′ end processing signals which instruct the 3′ end processing exist in 3′-UTR. 3′-UTR not only controls mRNA stability and the rate of mRNA degradation, but also helps to recognize UGA codon which directs the incorporation of rare selenocysteine into proteins. Still, many other signals existing in 3′-UTR determine mRNA localization, regulate translation initiation and translation efficiency as well as translation time, sites, etc.
