CAJ | 학술논문

对4年间6家医院所有门急诊有关敌敌畏、甲胺磷、乐果三种有机磷农药中毒病例进行了调查分析。运用气相色谱法对其血液中的浓度进行测定。采用Bliss法，计算其死亡率和昏迷率的加权直线回归方程，并获得其经救治后血液半数致死浓度LC50、半数致昏迷浓度CC50。综合文献和临床实践，认为及时的救治对中毒病例的治疗转归有较大影响，其自然的血液半数致死浓度应在经救治的半数致死浓度LC50和半数致昏述浓度之间。综合半数致死浓度和半数致昏迷浓度，计算其自然的半数致死浓度LCe50值。
대4년간6가의원소유문급진유관활활외、갑알린、악과삼충유궤린농약중독병례진행료조사분석。운용기상색보법대기혈액중적농도진행측정。채용Bliss법，계산기사망솔화혼미솔적가권직선회귀방정，병획득기경구치후혈액반수치사농도LC50、반수치혼미농도CC50。종합문헌화림상실천，인위급시적구치대중독병례적치료전귀유교대영향，기자연적혈액반수치사농도응재경구치적반수치사농도LC50화반수치혼술농도지간。종합반수치사농도화반수치혼미농도，계산기자연적반수치사농도LCe50치。
Total cases of organophosphorous（ dichlorvos、 methamidophos、 dimethoate） poisoning outpatients from six hospitals during four years were collected consecutively for lethal blood concentration study. Blood samples were detected with gas chromatography. The probabilities of death, coma were analyzed with Bliss method and their linear regressive equations of probit were obtained respectively, their 50％ lethal concentrations(LC50) and 50％ coma concentrations(CC50) were calculated by the formulas above. As the death rate was influenced by therapy, its natural death probability has been discussed and estimated their natural LC50 were between the LC50 and CC50 themselves. Combined LC50 and CC50, their natural LC50 were calculated.