CAJ | 학술논문

Th17细胞是近年来发现的一种新的效应T细胞亚群,在自身免疫性疾病和感染中发挥重要的作用,其分泌产生几种致炎细胞因子,包括新发现的细胞因子白细胞介素 17.Th17产生的细胞因子与Thl、Th2不同并且与其相互对抗.Th17细胞很可能对防御胞外病原菌的感染及自身免疫性疾病产生影响.综述了Th17细胞产生的细胞因子及其在肺部感染免疫中的作用相关方面的进展.
Th17세포시근년래발현적일충신적효응T세포아군,재자신면역성질병화감염중발휘중요적작용,기분비산생궤충치염세포인자,포괄신발현적세포인자백세포개소 17.Th17산생적세포인자여Thl、Th2불동병차여기상호대항.Th17세포흔가능대방어포외병원균적감염급자신면역성질병산생영향.종술료Th17세포산생적세포인자급기재폐부감염면역중적작용상관방면적진전.
Th17 (T helper 17 cel1), a newly discovered subpopulation of T lymphocytes, was confirmed to play a critical role in inflammatory and autoimmune diseases. This subpopulation produces several proinflammatory cytokines including a novel interleukin named as IL-17. The cytokines produced by Th17 cells differed from those by and Th1 and Th2 cells, and exhibits antagonistic effects among them. Th17 cells are probably effective to resist infections caused by extracellular bacteria. This paper discussed the cytokines produced by th17 cells and the function of cytokins in immunity against pulmonary infection.