CAJ | 학술논문

目的观察动态血糖监测系统(CGMS)监测常规多次皮下胰岛素注射(MSII)与胰岛素泵持续皮下胰岛素注射(CSII)治疗老年2型糖尿病鼻饲患者的降糖效果及安全性.方法将67例老年糖尿病患者随机分为CSII组(n=34)及MSII组(n=33).以CGMS观察治疗2 w后血糖谱的变化,比较2种治疗方法在全天血糖曲线变化、控制血糖水平、低血糖发生率方面的差别.结果 CSII组血糖控制效果明显优于MSII组(P<0.05,P<0.01),低血糖发生率也低于MSII组(P<0.01).结论 CSII治疗使糖尿病鼻饲患者全天血糖曲线波动小,血糖控制更为平稳,可减少低血糖的发生.
목적 관찰동태혈당감측계통(CGMS)감측상규다차피하이도소주사(MSII)여이도소빙지속피하이도소주사(CSII)치료노년2형당뇨병비사환자적강당효과급안전성.방법 장67례노년당뇨병환자수궤분위CSII조(n=34)급MSII조(n=33).이CGMS관찰치료2 w후혈당보적변화,비교2충치료방법재전천혈당곡선변화、공제혈당수평、저혈당발생솔방면적차별.결과 CSII조혈당공제효과명현우우MSII조(P<0.05,P<0.01),저혈당발생솔야저우MSII조(P<0.01).결론 CSII치료사당뇨병비사환자전천혈당곡선파동소,혈당공제경위평은,가감소저혈당적발생.
Objective To investigate the superiority of insulin pumps on the treatment of nasal feeding diabetes mellitus(DM) by continuous glucose monitoring system(CGMS). Methods 67 elderly DM patients were divided into CSII and multiple subcutaneous insulin injection (MSII) groups randomly. CSII group had 34 cases which were given insulin pumps and MSII had 33 cases which were given MSII methods. The daily blood glucose profiles were observed after treatment for 2 w by CGMS. Results The therapeutic effect of blood controlling in CSII group was superiority to that in MSII group(P＜0.05,P＜0.01), and the incidence of hypoglycemia was lower than that in MSII group(P＜0.01). Conclusions Insulin pumps shows less nocturnal hypoglycemia and more stable blood glucose profile with less excursion.