中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2010年
4期
409-413
,共5页
王红美%苏英迪%黄曼%江苏娟%吴柳坚%王善青
王紅美%囌英迪%黃曼%江囌娟%吳柳堅%王善青
왕홍미%소영적%황만%강소연%오류견%왕선청
碘%缺乏症%甲状腺肿,地方性%数据收集
碘%缺乏癥%甲狀腺腫,地方性%數據收集
전%결핍증%갑상선종,지방성%수거수집
Iodine%Deficiency disorders%Goiter,Endemic%Data collection
目的 了解海南省缺碘高危地区碘缺乏病防治现状和防治措施落实效果.方法 2007-2009年,采用典型抽样方法,在海南省碘盐覆盖率低的8个市(县),以乡为单位搜索10岁以下新发地方性克汀病(地克病)患儿;在乡小学校,抽取8~10岁儿童,采用触诊、B超法检查儿童甲状腺;收集儿童尿样;测定儿童智商(IQ);对五年级学生进行健康教育问卷调查.入户采集育龄妇女尿样和家中食用盐样,同时对妇女进行健康教育问卷调查.尿碘测定采用砷铈催化分光光度法,盐碘测定采用半定量法,IQ测定采用中国联合型瑞文测验(CRT-C2).结果 共调查72个乡(镇),其中8~10儿童7937名、育龄妇女1797名、5年级学生4128名,线索调查发现疑似新发地克病患儿1例.居民碘盐覆盖率由2007年的44.6%(629/1411)提高到2009年的92.1%(1688/1832).儿童甲状腺肿大(甲肿)率触诊法、B超法由2007年的5.9%(269/4548)、6.0%(274/4548)下降到2009年的1.6%(24/1461)、0.1%(2/1461);尿碘中位数由2007年的97.4μg/L上升2009年165.0μg/L;尿碘<50.0μg/L和<100.0μg/L的比例由2007年的21.4%(973/4548)、51.2%(2329/4548)下降到2009年的75%(110/1461)、23.4%(342/1461);育龄妇女尿碘中位数由2007年的73.7μg/L上升到2009年的126.1μg/L,其中孕妇的尿碘中位数由2007年的55.7μg/L上升到2008年117.9μg/L、2009年的121.5 μg/L,但仍<150.0μg/L.五年级学生、育龄妇女碘缺乏病的健康教育问卷调查及格率分别由2007年29.8%(446/1495)、24.1%(179/742)提高到2009年65.8%(732/1112)、72.1%(264/366).儿童IQ值为90.4±16.0,IQ低下(≤69)的比例为12.6%(1000/7937).结论 海南省高危地区碘缺乏病病情逐年改善,但孕妇碘营养水平仍较低,今后应加强对孕妇的补碘.
目的 瞭解海南省缺碘高危地區碘缺乏病防治現狀和防治措施落實效果.方法 2007-2009年,採用典型抽樣方法,在海南省碘鹽覆蓋率低的8箇市(縣),以鄉為單位搜索10歲以下新髮地方性剋汀病(地剋病)患兒;在鄉小學校,抽取8~10歲兒童,採用觸診、B超法檢查兒童甲狀腺;收集兒童尿樣;測定兒童智商(IQ);對五年級學生進行健康教育問捲調查.入戶採集育齡婦女尿樣和傢中食用鹽樣,同時對婦女進行健康教育問捲調查.尿碘測定採用砷鈰催化分光光度法,鹽碘測定採用半定量法,IQ測定採用中國聯閤型瑞文測驗(CRT-C2).結果 共調查72箇鄉(鎮),其中8~10兒童7937名、育齡婦女1797名、5年級學生4128名,線索調查髮現疑似新髮地剋病患兒1例.居民碘鹽覆蓋率由2007年的44.6%(629/1411)提高到2009年的92.1%(1688/1832).兒童甲狀腺腫大(甲腫)率觸診法、B超法由2007年的5.9%(269/4548)、6.0%(274/4548)下降到2009年的1.6%(24/1461)、0.1%(2/1461);尿碘中位數由2007年的97.4μg/L上升2009年165.0μg/L;尿碘<50.0μg/L和<100.0μg/L的比例由2007年的21.4%(973/4548)、51.2%(2329/4548)下降到2009年的75%(110/1461)、23.4%(342/1461);育齡婦女尿碘中位數由2007年的73.7μg/L上升到2009年的126.1μg/L,其中孕婦的尿碘中位數由2007年的55.7μg/L上升到2008年117.9μg/L、2009年的121.5 μg/L,但仍<150.0μg/L.五年級學生、育齡婦女碘缺乏病的健康教育問捲調查及格率分彆由2007年29.8%(446/1495)、24.1%(179/742)提高到2009年65.8%(732/1112)、72.1%(264/366).兒童IQ值為90.4±16.0,IQ低下(≤69)的比例為12.6%(1000/7937).結論 海南省高危地區碘缺乏病病情逐年改善,但孕婦碘營養水平仍較低,今後應加彊對孕婦的補碘.
목적 료해해남성결전고위지구전결핍병방치현상화방치조시락실효과.방법 2007-2009년,채용전형추양방법,재해남성전염복개솔저적8개시(현),이향위단위수색10세이하신발지방성극정병(지극병)환인;재향소학교,추취8~10세인동,채용촉진、B초법검사인동갑상선;수집인동뇨양;측정인동지상(IQ);대오년급학생진행건강교육문권조사.입호채집육령부녀뇨양화가중식용염양,동시대부녀진행건강교육문권조사.뇨전측정채용신시최화분광광도법,염전측정채용반정량법,IQ측정채용중국연합형서문측험(CRT-C2).결과 공조사72개향(진),기중8~10인동7937명、육령부녀1797명、5년급학생4128명,선색조사발현의사신발지극병환인1례.거민전염복개솔유2007년적44.6%(629/1411)제고도2009년적92.1%(1688/1832).인동갑상선종대(갑종)솔촉진법、B초법유2007년적5.9%(269/4548)、6.0%(274/4548)하강도2009년적1.6%(24/1461)、0.1%(2/1461);뇨전중위수유2007년적97.4μg/L상승2009년165.0μg/L;뇨전<50.0μg/L화<100.0μg/L적비례유2007년적21.4%(973/4548)、51.2%(2329/4548)하강도2009년적75%(110/1461)、23.4%(342/1461);육령부녀뇨전중위수유2007년적73.7μg/L상승도2009년적126.1μg/L,기중잉부적뇨전중위수유2007년적55.7μg/L상승도2008년117.9μg/L、2009년적121.5 μg/L,단잉<150.0μg/L.오년급학생、육령부녀전결핍병적건강교육문권조사급격솔분별유2007년29.8%(446/1495)、24.1%(179/742)제고도2009년65.8%(732/1112)、72.1%(264/366).인동IQ치위90.4±16.0,IQ저하(≤69)적비례위12.6%(1000/7937).결론 해남성고위지구전결핍병병정축년개선,단잉부전영양수평잉교저,금후응가강대잉부적보전.
Objective To know the prevalence of iodine deficiency disorders(IDD) and the implementation of control measures against the disorders in high-risk areas of Hainan province. Methods Typical sampling principle was used. Eight townships with lower coverage rate of iodized salt were chosen in IDD high-risk counties of Hainan. New cretinism cases were screened among children aged 10 years and under. Intelligence quotient (IQ)value, urinary iodine (UI) concentration and thyroid gland size (by palpation and B ultrasonic) were investigated in children aged 8 to 10 years and questionnaire was also carried out among students from grade 5 in elementary school. Edible salt and urine of women of childbearing age were collected to detect iodine levels, respectively,questionnaire was also carried out among the women of childbearing age. The UI was determined by As3-Ce4+ catalytic spectrophotometer, the salt iodine level was determined using self-quantitative kit. IQ values were measured by the Combined Raven Test in China (CRT-C2). Results Seventy-two townships were investigated in three consecutive years, 7937 children aged 8 to 10 years, 1797 women of childbearing age and 4128 students of grade 5 were included in the survey. One child was diagnosed as suspected new cretinism case. The coverage rate of iodized salt was increased from 44.6%(629/1411) in 2007 to 92.1%(1688/1832) in 2009. The goiter rate was dropped from 5.9% (269/4548), 6.0% (274/4548) in 2007 to 1.6% (24/1461), 0.1% (2/1461) in 2009 bypalpation, and by B-ultrasound, respectively, in children aged 8 to 10 years. The median urinary iodine(MUI) was found to be increased from 97.4 μg/L in 2007 to 165.0 μg/L in 2009, and the percentage of UI less than 50.0 μg/L, and 100.0 μg/L were dropped from 21.4%(973/4548), 51.2%(2329/4548) in 2007 to 7.5 %(110/1461), 23.4%(342/1461) in 2009, respectively. The MUI of women of childbearing age was found to be elevated from 73.7 μg/L in 2007 to 126.1 μg/L in 2009, and the value was also increased from 55.7 μg/L to 121.5 μg/L in pregnant women, but these values were still lower than 150.0 μg/L The pass rate of the questionnaire of IDD controlling among the students of grade 5 and the women of childbearing age was raised from 29.8% (446/1495) ,24.1% (179/742) in 2007 to 65.8%(732/1112), 72.1%(264/366) in 2009, respectively. The mean IQ of children was 90.4±16.0, and the percentage of IQ value less than 69 was 12.6% (1000/7937). Conclusions The diseased state of IDD has improved in the high-risk counties of disorders in Hainan province, but the pregnant women are still iodine deficient. Iodine supplimentation should be promoted among pregnant women.