CAJ | 학술논문

妇科肿瘤年轻患者经治疗后常因卵巢功能衰退提前出现绝经综合征,其最有效的治疗方法是激素替代治疗(HRT).根据目前的研究,HRT不增加早期子宫内膜癌、子宫平滑肌肉瘤复发及死亡风险；对卵巢癌患者的安全性尚无定论；宫颈鳞癌、阴道癌和外阴癌不是HRT的禁忌证；但雌激素替代治疗(ERT)是低度恶性子宫内膜间质肉瘤的禁忌.对有严重绝经综合征的患者,可综合评估风险,与患者充分沟通后使用HRT以提高生活质量.
부과종류년경환자경치료후상인란소공능쇠퇴제전출현절경종합정,기최유효적치료방법시격소체대치료(HRT).근거목전적연구,HRT불증가조기자궁내막암、자궁평활기육류복발급사망풍험；대란소암환자적안전성상무정론；궁경린암、음도암화외음암불시HRT적금기증；단자격소체대치료(ERT)시저도악성자궁내막간질육류적금기.대유엄중절경종합정적환자,가종합평고풍험,여환자충분구통후사용HRT이제고생활질량.
Treatment of gynaeeological cancer frequently results in the loss of ovarian function and menopausal syndrome.The most effective treatment is hormone replacement therapy (HRT).According to the current studies,HRT does not increase the risk of recurrence or death in patients with early stage endometrial cancer and uterine leiomyosarcomas. The safety of HRT in ovarian cancer patients is inconclusive. Cervical squamous cell carcinoma, vaginal cancer and vulvar cancer are not contraindications for HRT. Estrogen replacement therapy (ERT) is contraindicated for low-grade endometrial stromal sarcomas. Therefore,after integrated risk assessment and discussion,patients with severe menopausal symptoms can be treated with HRT to improve the quality of life.