CAJ | 학술논문

患者男,15岁,颜面、双上肢、指趾、甲沟反复间断出现红色分泌物10月余就诊.就诊前患者因受精神刺激后,颜面部出现红色分泌物.以耳、眼、鼻周为甚,每次发作持续2～3 min自行停止,并形成凝血痂,间歇期无一定的规律,长则月余,短则10天左右.发作期间每日 1～4次,持续1周左右.局部皮肤不伴有瘙痒、疼痛,擦拭血迹后皮肤无瘀点、瘀斑及创口.发作前患者伴有烦躁、易怒、易激惹等精神症状,偶有兴奋及入睡困难,夜间不发作.多次发作后双前臂、小腿伸侧、指趾、甲周也相继出现同样的红色分泌物,多为单一部位对称性发生,交替出现.汗血涂片与外周血成分一致.诊断为血汗症.实验室、病理组织、投射电镜及影像学检查均无异常发现.该患者以维生素C、复方芦丁片及谷维素治疗,效果均不满意.血汗症是一种少见的疾病,探讨其发病机制是治疗此病的关键.
환자남,15세,안면、쌍상지、지지、갑구반복간단출현홍색분비물10월여취진.취진전환자인수정신자격후,안면부출현홍색분비물.이이、안、비주위심,매차발작지속2～3 min자행정지,병형성응혈가,간헐기무일정적규률,장칙월여,단칙10천좌우.발작기간매일 1～4차,지속1주좌우.국부피부불반유소양、동통,찰식혈적후피부무어점、어반급창구.발작전환자반유번조、역노、역격야등정신증상,우유흥강급입수곤난,야간불발작.다차발작후쌍전비、소퇴신측、지지、갑주야상계출현동양적홍색분비물,다위단일부위대칭성발생,교체출현.한혈도편여외주혈성분일치.진단위혈한증.실험실、병리조직、투사전경급영상학검사균무이상발현.해환자이유생소C、복방호정편급곡유소치료,효과균불만의.혈한증시일충소견적질병,탐토기발병궤제시치료차병적관건.
A 15-year-old male patient presented with intermittent red secretion on the face, upper limbs, nail grooves, fingers and toes for more than 10 months. Ten months prior to the presentation, red secre-tions began to emerge on the face, especially ears, eyes and the surrounding area of nose, following a severe psychical stimulus. The attack typically lasted 2-3 minutes before spontaneous stop with the formation of blood crusts. The frequency was 1-4 per day during the attack of hemathidrosis which might last 1 week. The interval was irregular and varied from 10 days to months. There was no blood stasis, bruise or wound left on the skin after the wipe of bloodstain, and no itch or pain was complained of. Before the secretion of bloody sweat, the patient was always fidgety, irritable, and sometimes excited or difficult to sleep, but the secretion never occurred at night. After several episodes, bloody sweat also appeared in succession and symmetrically on the forearms, extensor crura, fingers, toes and perionychium. The cell components of bloody sweat were identical to those of peripheral blood. The patient was diagnosed as hemathidrosis. No abnormality was found in labora-tory tests, histopathological examination, electron microscopy or radiology. No relief of symptoms was achieved after treatment with vitamin C, rutoside and oryzanol. Hemathidrosis is a rare disease, and to clarify its patho-genesis is essential for its treatment.