CAJ | 학술논문

目的探讨伽玛刀治疗原发性三又神经痛的疗效.方法 2003年1月至2008年3月,我院应用伽玛刀治疗原发性三又神经痛120例;治疗靶点为三叉神经根,用4 mm准直器,靶点中心计量为80～90 Gy.疗效评估采用患者自我报告疼痛的控制程度及药物用量的变化.结果所有患者进行了随访,平均随访期(20.0±4.5)个月.本组病例中治愈69例(57.5%);显效34例(28.3%)、有效12例(10.0%)、无效5例(4.2%);总有效率为95.8%.5例患者疼痛复发后行其他治疗.83例患者(69.2%)曾出现一过性、局限性的面部麻木.14例患者(11.7%)在疼痛缓解后留下持续性的面部麻木;部分患者还伴有味觉减退、口嚼无力等主诉.结论伽玛刀治疗原发性三又神经痛能够显著缓解疼痛、提高生活质量,不良反应发生率较低:是一种较为理想的治疗方法.
목적 탐토가마도치료원발성삼우신경통적료효.방법 2003년1월지2008년3월,아원응용가마도치료원발성삼우신경통120례;치료파점위삼차신경근,용4 mm준직기,파점중심계량위80～90 Gy.료효평고채용환자자아보고동통적공제정도급약물용량적변화.결과 소유환자진행료수방,평균수방기(20.0±4.5)개월.본조병례중치유69례(57.5%);현효34례(28.3%)、유효12례(10.0%)、무효5례(4.2%);총유효솔위95.8%.5례환자동통복발후행기타치료.83례환자(69.2%)증출현일과성、국한성적면부마목.14례환자(11.7%)재동통완해후류하지속성적면부마목;부분환자환반유미각감퇴、구작무력등주소.결론 가마도치료원발성삼우신경통능구현저완해동통、제고생활질량,불량반응발생솔교저:시일충교위이상적치료방법.
Objective To evaluate the therapeutic efficacy of gamma knife in treatment of primary trigeminal neuralgia Methods Retrospectively analysis of 120 cases with primary trigeminal neuralgia treated by gamma knife in our department From Jan. 2003 to Mar. 2008 were performed. All cases were treated with the 4 mm collimator and targeted at the proximal nerve at the root entry zone located by MRI. The target dose varied from 80 -90 Gy. Results After a follow-up of 20. 0 ±4. 5 months, complete relief of pain occurred in 69 patients (57. 5%), 50% -90% relief in 34 (28. 3%), relief less than 50% in 12(10.0%) but no relief in 5(4.2 %).The efficient rate was 95. 8% . The common complications include numbness, absence of corneal reflex. 83 patients (69. 2%) experienced temporal facial numbness and 14 patients (11. 7%) reported continuous numbness after treatment of the gamma knife. Conclusions Gamma knife radiosurgery is a minimally invasive technique for the treatment of primary trigeminal neuralgia with few complications.