国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2011年
7期
581-583
,共3页
脑梗死%疏血通注射液%依达拉奉注射液
腦梗死%疏血通註射液%依達拉奉註射液
뇌경사%소혈통주사액%의체랍봉주사액
Cerebral infarction%Shuxuetong injection%Edaravone injection
目的 观察疏血通联合依达拉奉注射液对急性脑梗死患者神经功能、血脂、血清C-反应蛋白及IL-6水平的影响.方法 将100例急性脑梗死患者按照随机数字表法分为两组各50例,对照组给予依达拉奉注射液30 mg加入100 ml生理盐水中静滴,2次/d,连用14 d;治疗组在对照组基础上给予疏血通注射液6 mg加入250 ml生理盐水中静滴,1次/d,连用14 d.治疗结束后检测患者血脂TG、TC、LDL-C、HDL-C,及血清C-反应蛋白、IL-6水平,并进行神经功能评分.结果 与对照组比较,治疗组神经功能缺损评分明显降低(χ2=4.351,P<0.05);血清TG、TC、LDL-C水平(χ2分别为2.135,3.061,3.655,P均<0.05)、血清C-反应蛋白水平以及IL-6水平明显下降(χ2值分别为3.811,3.617,P均<0.05);血清HDL-C明显升高(χ2=2.762,P<0.01).治疗组总有效率为86.0%,对照组为66.0%,两组比较,差异有统计学意义(χ2=3.393,P<0.05).结论 采用疏血通联合依达拉奉注射液治疗急性脑梗死,疗效优于单纯应用依达拉奉注射液治疗.
目的 觀察疏血通聯閤依達拉奉註射液對急性腦梗死患者神經功能、血脂、血清C-反應蛋白及IL-6水平的影響.方法 將100例急性腦梗死患者按照隨機數字錶法分為兩組各50例,對照組給予依達拉奉註射液30 mg加入100 ml生理鹽水中靜滴,2次/d,連用14 d;治療組在對照組基礎上給予疏血通註射液6 mg加入250 ml生理鹽水中靜滴,1次/d,連用14 d.治療結束後檢測患者血脂TG、TC、LDL-C、HDL-C,及血清C-反應蛋白、IL-6水平,併進行神經功能評分.結果 與對照組比較,治療組神經功能缺損評分明顯降低(χ2=4.351,P<0.05);血清TG、TC、LDL-C水平(χ2分彆為2.135,3.061,3.655,P均<0.05)、血清C-反應蛋白水平以及IL-6水平明顯下降(χ2值分彆為3.811,3.617,P均<0.05);血清HDL-C明顯升高(χ2=2.762,P<0.01).治療組總有效率為86.0%,對照組為66.0%,兩組比較,差異有統計學意義(χ2=3.393,P<0.05).結論 採用疏血通聯閤依達拉奉註射液治療急性腦梗死,療效優于單純應用依達拉奉註射液治療.
목적 관찰소혈통연합의체랍봉주사액대급성뇌경사환자신경공능、혈지、혈청C-반응단백급IL-6수평적영향.방법 장100례급성뇌경사환자안조수궤수자표법분위량조각50례,대조조급여의체랍봉주사액30 mg가입100 ml생리염수중정적,2차/d,련용14 d;치료조재대조조기출상급여소혈통주사액6 mg가입250 ml생리염수중정적,1차/d,련용14 d.치료결속후검측환자혈지TG、TC、LDL-C、HDL-C,급혈청C-반응단백、IL-6수평,병진행신경공능평분.결과 여대조조비교,치료조신경공능결손평분명현강저(χ2=4.351,P<0.05);혈청TG、TC、LDL-C수평(χ2분별위2.135,3.061,3.655,P균<0.05)、혈청C-반응단백수평이급IL-6수평명현하강(χ2치분별위3.811,3.617,P균<0.05);혈청HDL-C명현승고(χ2=2.762,P<0.01).치료조총유효솔위86.0%,대조조위66.0%,량조비교,차이유통계학의의(χ2=3.393,P<0.05).결론 채용소혈통연합의체랍봉주사액치료급성뇌경사,료효우우단순응용의체랍봉주사액치료.
Objective To observe effects of shuxuetong injection combined with edaravone injection on the neurological, sermn lipid, c-reactive protein and interleukin 6 Levels in serum in patients with acute cerebral infarction. Methods 100 patients with acute cerebral infarction were randomly recruited into a control group and a treatment group by means of random number table. The control group was treated with 30mg edaravone injection, which was added to 100 ml normal saline, twice a day, continuous therapy for 14 days, and the treatment group was treated with 6mg shuxuetong injection, which was added to 2S0 ml normal saline, once a day, continuous therapy for 14 days based on the control group. The neurological was observed, triglyceride (TG) , cholesterol (TO , low density lipoprotein cholesterol (LDL-C) , high density lipoprotein cholesterol (HDL-C) , c-reactive protein and interleukin 6 Levels in serum were detected before and after the treatment.Results Compared with the control group, neurological deficit score, c-reactive protein and interleukin 6 Levels in serum in the treatment group decreased significantly (χ2=4.351, 3.81, 3.617 respectively, P<0.05) .TG, TC, LDL-C in serum in the treatment group were lower than that of the control group (χ2=2.135,P<0.01; χ2=3.061, 3.655, P<0.05 ); HDL-C in serum was higher than that of the control group (χ2=2.762,P<0.01) . The total effective rate of the treatment group and the control group was 86.0% and 66.0% respectively, there was a significant difference (χ2=3.393, P<0.05) . Conclusion Shuxuetong injection combined with edaravone injection is better than edaravone injection to treat acute cerebral infarction.
