CAJ | 학술논문

目的探讨脑梗死患者情景记忆编码损伤及其相关影响因素.方法急性期病情稳定的脑梗死患者(112例),与正常对照组(115例)比较.各组均按要求在计算机上完成情景记忆编码测试,观察各组情景记忆编码成绩的变化以及相关因素的影响.结果脑梗死组情景记忆编码成绩记住数(REM)明显低于对照组[(70.81±6.08)%,(84.67±4.49)%,P＜0.01)];额叶梗死组、颞叶梗死组、基底节梗死组及放射冠梗死组四组REM差异具有显著性[(65.88±5.73)%,(68.92±4.65)%,(73.39±6.20)%,(73.53±3.44)%,P＜0.01)],额叶梗死组低于颞叶梗死组(P＜0.05),颞叶梗死组低于基底节区梗死组及放射冠梗死组(P＜0.05,P＜0.01);皮层梗死组低于皮层下梗死组[(67.37±5.40)%,(73.46±4.99)%,(P＜0.01)].脑梗死小病灶组REM高于脑梗死大病灶组[(72.67±4.47)%,(67.56±6.18)%,P＜0.01)],且病灶直径大小与REM具有显著相关性(r=-0.39).对照组、脑梗死伴脑萎缩与脑梗死无脑萎缩三组REM差异具有显著性(P＜0.01),脑梗死伴脑萎缩组REM低于脑梗死无脑萎缩组和对照组,差异具有显著性(均P＜0.01);脑梗死无脑萎缩组REM低于对照组,差异具有显著性(P＜0.01).结论脑梗死患者存在情景记忆编码损害,梗死部位、梗死灶大小以及有无脑萎缩与情景记忆编码损害有关.
목적 탐토뇌경사환자정경기억편마손상급기상관영향인소.방법 급성기병정은정적뇌경사환자(112례),여정상대조조(115례)비교.각조균안요구재계산궤상완성정경기억편마측시,관찰각조정경기억편마성적적변화이급상관인소적영향.결과 뇌경사조정경기억편마성적기주수(REM)명현저우대조조[(70.81±6.08)%,(84.67±4.49)%,P＜0.01)];액협경사조、섭협경사조、기저절경사조급방사관경사조사조REM차이구유현저성[(65.88±5.73)%,(68.92±4.65)%,(73.39±6.20)%,(73.53±3.44)%,P＜0.01)],액협경사조저우섭협경사조(P＜0.05),섭협경사조저우기저절구경사조급방사관경사조(P＜0.05,P＜0.01);피층경사조저우피층하경사조[(67.37±5.40)%,(73.46±4.99)%,(P＜0.01)].뇌경사소병조조REM고우뇌경사대병조조[(72.67±4.47)%,(67.56±6.18)%,P＜0.01)],차병조직경대소여REM구유현저상관성(r=-0.39).대조조、뇌경사반뇌위축여뇌경사무뇌위축삼조REM차이구유현저성(P＜0.01),뇌경사반뇌위축조REM저우뇌경사무뇌위축조화대조조,차이구유현저성(균P＜0.01);뇌경사무뇌위축조REM저우대조조,차이구유현저성(P＜0.01).결론 뇌경사환자존재정경기억편마손해,경사부위、경사조대소이급유무뇌위축여정경기억편마손해유관.
Objective To investigate the impairment and the effect factors of encoding of episodic memory in patients with cerebral infarction. Methods 112 cases cerebral infarction patients and 115 healthy elders as controls were tested for episodic memory encoding with episodic pictures accomplished in computer, and compare the differences of encoding of episodic memory between the two groups. Results The remember indexes ( REM )of encoding memory test in patient group was significantly lower than that in control group( (70.81 ± 6.08 )vs (84.67 ± 4.49), P ＜ 0.01 ). The REM in patients with different impaired areas was significantly different ( (65.88 ± 5.73 ), (68.92 ± 4.65 ), (73.39 ± 6.20), ( 73.53 ± 3.44), P ＜ 0. 01 ). The REM in frontal lobe infarction group was significantly lower than that in temporal lobe infarction group (P ＜ 0.05 ), and in temporal lobe infarction group was significantly lower than that in basal ganglia infarction group and corona radiate infarction group (P＜0.05, P＜0. 01). The REM in cortex infarction group was significantly lower than that in under cortex group ( ( 67.37 ± 5.40 ), ( 73.46 ± 4.99 ), P ＜ 0.01 ). The REM in small cerebral infarction group was significantly higher than that in large cerebral infarction group( (72.67 ±4.47 ), (67.56 ± 6.18 ), P＜0.01 ). The size of cerebral infarction diameter was related with the REM( r= -0.39, P＜0. 01 ). The REM among control group,infarction with atrophy group, and infarction without atrophy group were significantly different( (67.03 ± 6. 17 ),( 72.84 ± 5. 00 ), ( 84.67 ± 4.49 ), P ＜ 0. 01 ). The REM in infarction with atrophy group was significantly lower than that in infarction without atrophy group and control group( both P＜0.01 ) ,The REM in infarction without atrophy group was significantly lower than that in control group (P ＜ 0.01). Conclusion The encoding of episodic memory was impaired in cerebral infarction patients. The infarction parts,size of infarction area and atrophy was related with the impairment of encoding of episodic memory.