中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2010年
8期
884-887
,共4页
赵军%成洪波%黄丽娜%罗润来
趙軍%成洪波%黃麗娜%囉潤來
조군%성홍파%황려나%라윤래
青光眼%混合型%机制
青光眼%混閤型%機製
청광안%혼합형%궤제
Glaucoma%Mixed%Mechanism
目的 分析混合型青光眼(mixed glaucoma,MG)住院病人的致病机制.方法 收集 2005年~2009年连续住院患者MG 109只眼(76例)的临床资料,结合眼压、C/D、视野、前房角镜及超声生物显微镜(ultrasound biomicroscopy,UBM)等临床资料,分类分析其混合致病机制的构成.结果 (1)本组病例存在12个致病机制类型:原发性开角型青光眼(primary open-angle glaucoma,POAG、原发性闭角型青光眼(primary angle-closure glaucoma,PACG)、先天性青光眼、新生血管性青光眼、青睫综合征及以下因素:晶状体膨胀或脱位、睫状体囊肿、糖皮质激素、眼外伤或眼内手术、虹膜炎、Fuchs综合征和剥脱综合征继发性青光眼.(2) 本组病例存在7类混合机制致病:POAG合并PACG35只眼,占32.1%;PACG合并继发性闭角型青光眼32只眼(29.4%);PACG合并继发性开角型青光眼13只眼(11.9%);POAG合并继发性开角型青光眼11只眼(10.1%);POAG合并继发性闭角型青光眼10只眼(9.2%);先天性青光眼合并继发性青光眼5只眼(4.6%)及不同类型的继发性青光眼合并存在3只眼(2.8%).结论 注意对青光眼发病机制的全面分析,避免明确一种青光眼致病病机制而忽略混合致病机制的存在,以便采取恰当全面的治疗方案;UBM的应用有助于MG致病机制的分析;POAG 合并PACG是MG的主要类型.
目的 分析混閤型青光眼(mixed glaucoma,MG)住院病人的緻病機製.方法 收集 2005年~2009年連續住院患者MG 109隻眼(76例)的臨床資料,結閤眼壓、C/D、視野、前房角鏡及超聲生物顯微鏡(ultrasound biomicroscopy,UBM)等臨床資料,分類分析其混閤緻病機製的構成.結果 (1)本組病例存在12箇緻病機製類型:原髮性開角型青光眼(primary open-angle glaucoma,POAG、原髮性閉角型青光眼(primary angle-closure glaucoma,PACG)、先天性青光眼、新生血管性青光眼、青睫綜閤徵及以下因素:晶狀體膨脹或脫位、睫狀體囊腫、糖皮質激素、眼外傷或眼內手術、虹膜炎、Fuchs綜閤徵和剝脫綜閤徵繼髮性青光眼.(2) 本組病例存在7類混閤機製緻病:POAG閤併PACG35隻眼,佔32.1%;PACG閤併繼髮性閉角型青光眼32隻眼(29.4%);PACG閤併繼髮性開角型青光眼13隻眼(11.9%);POAG閤併繼髮性開角型青光眼11隻眼(10.1%);POAG閤併繼髮性閉角型青光眼10隻眼(9.2%);先天性青光眼閤併繼髮性青光眼5隻眼(4.6%)及不同類型的繼髮性青光眼閤併存在3隻眼(2.8%).結論 註意對青光眼髮病機製的全麵分析,避免明確一種青光眼緻病病機製而忽略混閤緻病機製的存在,以便採取恰噹全麵的治療方案;UBM的應用有助于MG緻病機製的分析;POAG 閤併PACG是MG的主要類型.
목적 분석혼합형청광안(mixed glaucoma,MG)주원병인적치병궤제.방법 수집 2005년~2009년련속주원환자MG 109지안(76례)적림상자료,결합안압、C/D、시야、전방각경급초성생물현미경(ultrasound biomicroscopy,UBM)등림상자료,분류분석기혼합치병궤제적구성.결과 (1)본조병례존재12개치병궤제류형:원발성개각형청광안(primary open-angle glaucoma,POAG、원발성폐각형청광안(primary angle-closure glaucoma,PACG)、선천성청광안、신생혈관성청광안、청첩종합정급이하인소:정상체팽창혹탈위、첩상체낭종、당피질격소、안외상혹안내수술、홍막염、Fuchs종합정화박탈종합정계발성청광안.(2) 본조병례존재7류혼합궤제치병:POAG합병PACG35지안,점32.1%;PACG합병계발성폐각형청광안32지안(29.4%);PACG합병계발성개각형청광안13지안(11.9%);POAG합병계발성개각형청광안11지안(10.1%);POAG합병계발성폐각형청광안10지안(9.2%);선천성청광안합병계발성청광안5지안(4.6%)급불동류형적계발성청광안합병존재3지안(2.8%).결론 주의대청광안발병궤제적전면분석,피면명학일충청광안치병병궤제이홀략혼합치병궤제적존재,이편채취흡당전면적치료방안;UBM적응용유조우MG치병궤제적분석;POAG 합병PACG시MG적주요류형.
Objective To analyze the pathogenic mechanism in hospitalized patients with mixed glaucoma. Methods The clinical data of 76 cases (109 eyes) in hospitalized patients with mixed glaucoma from 2005 to 2009 were collected. The compositions of the pathogenic mechanism were analyzed according to intraocular pressure, the ratio of C/D, the results of visual field, gonioscope and ultrasound biomicroscopy (UBM). Results There were 12 pathogenic mechanisms in the cases including PACG, POAG, congenital glaucoma, neovascular glaucoma, glaucomatocyclitic syndrome, and Fuchs syndrome, iriditis, ocular trauma, swelling crystal body, cysts in the ciliary body, exofoliation syndrome and corticosteroid-induced glaucoma. There were 7 mixed mechanisms in the cases including POAG combined with PACG (35 eyes, 32.1%); PACG combined with secondary angle-closure glaucoma (32 eyes, 29.4 %); PACG combined with secondary open-angle glaucoma (13 eyes, 11.9%); POAG combined with secondary open-angle glaucoma (11 eyes, 10.1 %); POAG combined with secondary angle-closure glaucoma (10 eyes, 9.2 %); congenital glaucoma combined with secondary glaucoma (5 eyes, 4.6%) and secondary glaucoma combined with another secondary glaucoma (3 eyes, 2.8%). Conclusions The multi-analysis of pathogenic mechanisms in patients with glaucoma is very essential in order to choose appropriate treatment. It is helpful for analyzing the pathogenic mechanism of MG with UBM. The main type of MG is POAG combined with PACG.
