CAJ | 학술논문

目的探讨直肠癌根治性切除术后局部复发和远位转移的影响因素.方法使用Cox模型对我院1973年1月至2003年12月收治的160例直肠癌患者资料,并对其中152例根治手术切除的病例加以研究.着重分析此组患者复发、转移情况,对其中20个临床病理因素进行了详细的分析.结果本组患者男85例,女67例,随访率95.4%,手术切除率95.0%(152/160),术后的五年生存率48.0%(73/152).中位生存期为56.91个月.淋巴结转移情况Log rank χ~2值为120.02,原发癌侵犯深度为102.18、原发癌占据周径为83.39、癌体大体分型为76.16、癌体组织学分型为64.16、原发癌大小为47.66(均P<0.01).结论直肠癌根治性切除术后局部复发和远位转移的主要影响因素有6个,依次为淋巴结转移情况原发癌侵犯深度、原发癌占据周径、癌体大体分型、癌体组织分型、原发癌大小.
목적 탐토직장암근치성절제술후국부복발화원위전이적영향인소.방법 사용Cox모형대아원1973년1월지2003년12월수치적160례직장암환자자료,병대기중152례근치수술절제적병례가이연구.착중분석차조환자복발、전이정황,대기중20개림상병리인소진행료상세적분석.결과 본조환자남85례,녀67례,수방솔95.4%,수술절제솔95.0%(152/160),술후적오년생존솔48.0%(73/152).중위생존기위56.91개월.림파결전이정황Log rank χ~2치위120.02,원발암침범심도위102.18、원발암점거주경위83.39、암체대체분형위76.16、암체조직학분형위64.16、원발암대소위47.66(균P<0.01).결론 직장암근치성절제술후국부복발화원위전이적주요영향인소유6개,의차위림파결전이정황원발암침범심도、원발암점거주경、암체대체분형、암체조직분형、원발암대소.
Objective To investigate the influential factors of recurrence and distal metastasis after radical resection of rectal cancer. Methods The Cox model was used to analyze the information response in 160 cases of rectal cancer patients from January 1973 to December 2003. 152 cases of radical surgery cases were studied. 20 groups of clinical and pathological factors were analyzed. Results The follow-up rate was 95.4%. Surgical resec-tion rate was 95.0%. Five-year survival rate was 48.0% (73/152). Conclusion There were 6 influential factors of recurrence and distal metastasis after radical resection of rectal cancer:stages, primary tumor size, depth of inva-sion, lymph node metastasis and histological type.