CAJ | 학술논문

目的:探讨用脉冲震荡法(Impulse Oscillometry IOS)测定呼吸阻力在支气管激发试验中的诊断价值.方法:对72例门诊及住院就诊有自觉症状,临床怀疑为支气管哮喘而不能确诊的患者进行支气管激发试验,用IOS测定5～35赫兹震荡频率时的粘性阻力(R5-R35),5赫兹时的周边弹性阻力(X5),共振频率(Fres),阻抗(Zre),与常规通气一秒量(FEV1),呼气峰流速值(PEF),1秒率(FEV1/FVC%)进行对比研究.结果:支气管激发试验阳性组患者FEV1比试验前FEV1基础值降低20%的同时呼吸阻力明显增加,且阻力增加较FEV1下降出现早,部分支气管激发试验通气功能阴性的患者而阻力增加.结论:脉冲震荡法为一种新型肺功能测定方法,用于支气管激发试验可大大减少以往常规通气测定中的不足,对支气管激发试验阴性的患者在鉴别诊断上增加了新的内容.
목적:탐토용맥충진탕법(Impulse Oscillometry IOS)측정호흡조력재지기관격발시험중적진단개치.방법:대72례문진급주원취진유자각증상,림상부의위지기관효천이불능학진적환자진행지기관격발시험,용IOS측정5～35혁자진탕빈솔시적점성조력(R5-R35),5혁자시적주변탄성조력(X5),공진빈솔(Fres),조항(Zre),여상규통기일초량(FEV1),호기봉류속치(PEF),1초솔(FEV1/FVC%)진행대비연구.결과:지기관격발시험양성조환자FEV1비시험전FEV1기출치강저20%적동시호흡조력명현증가,차조력증가교FEV1하강출현조,부분지기관격발시험통기공능음성적환자이조력증가.결론:맥충진탕법위일충신형폐공능측정방법,용우지기관격발시험가대대감소이왕상규통기측정중적불족,대지기관격발시험음성적환자재감별진단상증가료신적내용.
Objective:To study the diagnostic value of using impulse oscillation (IOS) to measure the respiratory resistance in bronchial challenge test.Methods:72 patients who were suspicious of asthma were undergone bronchial challenge test, and patients' airway resistance, respiratory impedance, resonant frequency before and after challenge test were compared with that of FEV1, PEF, FEV1/FVC.Results:In positive challenge test group, who's FEV1 decreased more than 20%, patients' respiratory resistance increased significantly and increased earlier than the decreased of FEV1. In negative challenge test group who's FEV1 decreased less than 20%, some patients' respiratory resistance also increased.Conclusions:Using of impulse oscillation can reduce the limitation of ventilation test in bronchial challenge test, and it is more sensitive than ventilation test, so it is a new method for testing the pulmonary function.