CAJ | 학술논문

目的探讨持续小剂量伐地那非联合曲唑酮并配合心理行为治疗早泄的临床疗效.方法 136例早泄患者随机分为实验组(小剂量伐地那非+曲唑酮+行为疗法)和对照组(曲唑酮+行为疗法),记录治疗前后阴道内射精潜伏期(IELT)并进行组内和组间比较,同时记录夫妻对性生活的满意情况.结果治疗前,实验组和对照组IELT分别为(0.87±0.29)min、(0.93±0.35)min,治疗后分别为(4.62±2.31)min、(2.35±1.25)min,差异有统计学意义(P＜0.01),且实验组IELT较对照组相比差异有统计学意义(P＜0.01).夫妻双方对性生活的情况:实验组满意率(62.3%)和总满意率(满意加基本满意)(89.8%)分别优于对照组满意率(37.3%)和总满意率(67.2%),差异均有统计学意义(P＜0.01).结论持续小剂量伐地那非联合曲唑酮并配合心理行为治疗早泄在延长IELT,改善夫妻双方性生活满意度方面明显优于盐酸曲唑酮配合心理行为疗法组,持续小剂量给药可以起到增强疗效和降低副作用,两药合用在治疗早泄方面有一定的应用前景.
목적 탐토지속소제량벌지나비연합곡서동병배합심리행위치료조설적림상료효.방법 136례조설환자수궤분위실험조(소제량벌지나비+곡서동+행위요법)화대조조(곡서동+행위요법),기록치료전후음도내사정잠복기(IELT)병진행조내화조간비교,동시기록부처대성생활적만의정황.결과 치료전,실험조화대조조IELT분별위(0.87±0.29)min、(0.93±0.35)min,치료후분별위(4.62±2.31)min、(2.35±1.25)min,차이유통계학의의(P＜0.01),차실험조IELT교대조조상비차이유통계학의의(P＜0.01).부처쌍방대성생활적정황:실험조만의솔(62.3%)화총만의솔(만의가기본만의)(89.8%)분별우우대조조만의솔(37.3%)화총만의솔(67.2%),차이균유통계학의의(P＜0.01).결론 지속소제량벌지나비연합곡서동병배합심리행위치료조설재연장IELT,개선부처쌍방성생활만의도방면명현우우염산곡서동배합심리행위요법조,지속소제량급약가이기도증강료효화강저부작용,량약합용재치료조설방면유일정적응용전경.
Objective To evaluate the clinical efficacy of daily small dose Vardenafil and Trazodone combining with psychotherapy and physical training on treatment of premature ejaculation(PE). Methods Total of 136 patients with PE were randomly divided into two groups such as experimental group (small dose Vardenafil and Trazodone combining with behavior therapy) and control group (trazodone combining with behavior therapy). Intra-vaginal ejaculation latency times(IELT) of patients were detected and the coitus satisfaction of patients and their spouses were recorded before and after treatment. Results The IELTs of two groups were (0.87±0.29) and (0.93±0.35) minutes respectively before treatment, and (4.62±2.31) and (2.35±1.25) minutes respectively after treatment. There was a significant difference in IELTs between before treatment and after treatment (P＜0.01), furthermore there was also a significant difference in IELTs between experimental group and control group(P＜0.01).For satisfaction degree of sex life, better results were found in experimental group (62.3%) in comparison with that of control group (37.3%), (P＜0.01). Total satisfaction rate (satisfaction and basic satisfaction) was 89.8% and 67.2% in experimental group and control group, which existed a significant difference (P＜0.01).