中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
16期
2435-2437
,共3页
肝炎,乙型%血清标志物%乙型肝炎病毒DNA
肝炎,乙型%血清標誌物%乙型肝炎病毒DNA
간염,을형%혈청표지물%을형간염병독DNA
Hepatitis B%Serum markers%HBV-DNA
目的 探讨乙型肝炎(乙肝)患者血清标志物与其HBV-DNA水平之间的关系.方法 选取乙肝患者230例,用ELISA法检测血清标志物,用PCR法检测HBV-DNA水平.结果 在76例HBeAg阳性标本中,HBV-DNA阳性72例,阳性率为94.7％；154例HBeAg阴性标本中,HBV-DNA阳性72例,阳性率为46.7％.HBeAg阳性组与HBeAg阴性组HBV-DNA阳性率差异有统计学意义(P＜0.01).结论 乙肝患者血清标志物的检测,可以了解HBV在体内的感染情况,不能直接反映HBV在患者体内的复制情况.HBV-DNA水平检测可以更好地反映病毒的复制情况.
目的 探討乙型肝炎(乙肝)患者血清標誌物與其HBV-DNA水平之間的關繫.方法 選取乙肝患者230例,用ELISA法檢測血清標誌物,用PCR法檢測HBV-DNA水平.結果 在76例HBeAg暘性標本中,HBV-DNA暘性72例,暘性率為94.7％；154例HBeAg陰性標本中,HBV-DNA暘性72例,暘性率為46.7％.HBeAg暘性組與HBeAg陰性組HBV-DNA暘性率差異有統計學意義(P＜0.01).結論 乙肝患者血清標誌物的檢測,可以瞭解HBV在體內的感染情況,不能直接反映HBV在患者體內的複製情況.HBV-DNA水平檢測可以更好地反映病毒的複製情況.
목적 탐토을형간염(을간)환자혈청표지물여기HBV-DNA수평지간적관계.방법 선취을간환자230례,용ELISA법검측혈청표지물,용PCR법검측HBV-DNA수평.결과 재76례HBeAg양성표본중,HBV-DNA양성72례,양성솔위94.7％；154례HBeAg음성표본중,HBV-DNA양성72례,양성솔위46.7％.HBeAg양성조여HBeAg음성조HBV-DNA양성솔차이유통계학의의(P＜0.01).결론 을간환자혈청표지물적검측,가이료해HBV재체내적감염정황,불능직접반영HBV재환자체내적복제정황.HBV-DNA수평검측가이경호지반영병독적복제정황.
Objective To investigate the relationship between hepatitis B markers and HBV-DNA content.Methods 230 cases with hepatitis were selected.ELISA method was used to detect serum markers,PCR method for detecting the content of HBV-DNA.Results In 76cases of HBeAg positive specimens,72 cases were HBV-DNA positive,the positive rate was 94.7％ ; in 154 patients with HBeAg negative specimens,72 cases were HBV-DNA posifive,the positive rate was 46.7％.The difference between HBeAg positive group and HBeAg negative group was statistically different( P ＜0.01 ).Conclusion In patients with chronic hepatitis B,serum markers reflected,HBV can understand the in vivo infection,cannot directly reflect the in vivo replication of HBV.Detection of HBV-DNA content can better reflect the virus replication.
