CAJ | 학술논문

目的分析纤维板层型肝癌(FL-HCC)的临床表现、影像学特点及病理情况,提高对FL-HCC的认识.方法回顾性分析经手术治疗的2例FL-HCC患者的临床资料.结果 2例患者男女各1例,发病年龄均＜40岁,其中1例合并乙型肝炎感染,1例乙型肝炎病毒指标阴性,甲胎蛋白、癌胚抗原均正常,增强CT检查提示肿瘤动脉期明显强化,1例肿瘤内部见钙化.2例均成功行手术治疗,1例术后8个月肝内单病灶复发,1例随访16个月无复发.结论 FL-HCC临床少见,多见于青年人,多不合并乙型肝炎感染,影像学检查动脉期强化,门脉期去强化,可有肿瘤钙化.手术治疗是首选的治疗方法,术后预后较好.
목적 분석섬유판층형간암(FL-HCC)적림상표현、영상학특점급병리정황,제고대FL-HCC적인식.방법 회고성분석경수술치료적2례FL-HCC환자적림상자료.결과 2례환자남녀각1례,발병년령균＜40세,기중1례합병을형간염감염,1례을형간염병독지표음성,갑태단백、암배항원균정상,증강CT검사제시종류동맥기명현강화,1례종류내부견개화.2례균성공행수술치료,1례술후8개월간내단병조복발,1례수방16개월무복발.결론 FL-HCC림상소견,다견우청년인,다불합병을형간염감염,영상학검사동맥기강화,문맥기거강화,가유종류개화.수술치료시수선적치료방법,술후예후교호.
Objective To investigate the clinical features,imaging and pathologic findings of fibrolamellar hepatocellular carcinoma (FL-HCC).Methods Clinical data from 2 patients with FL-HCC confirmed by operation were analyzed retrospectively.Results There were 1 man and 1 woman,both of them were younger than 40 years.The man had hepatitis B,the woman did not have underlying hepatitis.The 2 patients had a normal hepatic function and α-fetoprotein level.Under dynamic contrast material-enhanced computed tomography,hepatic arterial phase CT images demonstrated heterogeneous enhancement of the tumor.Calcification was depicted in the CT images of 1 patients.Both of them underwent a successful operation.After 8 months of follow-up,1 patient had recurrence.And the other patient had no evidence of recurrence during 16 months follow-up time.Conclusion FL-HCC is a rare liver tumor that has distinct clinicopathologic features comparing with hepatocellular carcinoma.Most of FL-HCC occurs in young patients with normal level of α-fetoprotein and no history of hepatitis.Tumors may have calcification and become predominantly on hepatic arterial phase CT images.The most effective treatment for FL-HCC is surgical resection and prognosis is good.