CAJ | 학술논문

近年来,糖尿病发病率在全球呈快速增长的趋势,我国患病率已达到3%.多数Ⅰ型和部分Ⅱ型糖尿病患者需要采用外源性胰岛素注射控制血糖,患者不但要承受胰岛素注射带来的痛苦,而且还不可避免地要发生远期的并发症.因此,重建内源性胰岛分泌系统是近年来人们关注的热点.大量实验表明,胰腺移植不但可以中止胰岛素依赖性糖尿病并发症的发展,还可以转归已有的并发症,明显改善患者的预后.与其他器官移植一样,移植器官的获取及保存是移植成功的前提,由于胰腺组织的特殊性,不同的器官保存液对于保存胰腺效果不一.本文将对University of Wisconsin(UW)保存液在胰腺移植中作用作一论述.
근년래,당뇨병발병솔재전구정쾌속증장적추세,아국환병솔이체도3%.다수Ⅰ형화부분Ⅱ형당뇨병환자수요채용외원성이도소주사공제혈당,환자불단요승수이도소주사대래적통고,이차환불가피면지요발생원기적병발증.인차,중건내원성이도분비계통시근년래인문관주적열점.대량실험표명,이선이식불단가이중지이도소의뢰성당뇨병병발증적발전,환가이전귀이유적병발증,명현개선환자적예후.여기타기관이식일양,이식기관적획취급보존시이식성공적전제,유우이선조직적특수성,불동적기관보존액대우보존이선효과불일.본문장대University of Wisconsin(UW)보존액재이선이식중작용작일논술.
The incidence of diabetes has a rapid increase trend trend in the whole world. In China, the incidence has come to 3%. The most of patients with type Ⅰ and part of type Ⅱ diabetes rely on exogenious insulin to control blood glucose;they not only have to bear the uncomfortbleness of insulin injection, but also inevitably to face the forward complications, so,the main concern in recent years is to rebuild the endogenous insulin secretion system. Many experiments show that pancreas transplantation not only can stop the development of insulin dependent diabe-tes, but also revert the already existing complications, just like with other organ transplants, the organ access and preservation is prerequisite for success. Because of the specificity of pancreas tissue, the effects of different organ preservation solution for the preservation of the pancreas varies. In this paper we will talk about the effect of UW preservation solution in the pancreas transplantation.