CAJ | 학술논문

目的总结艾滋病恐惧症患者临床特征,初步提出艾滋病恐惧症的临床诊断依据.方法收集艾滋病恐惧症患者临床资料,分析研究对象的一般人口学、临床表现及实验室检测结果.结果艾滋病恐惧症患者临床特点包括:(1)可存在或不存在感染HIV的高危行为;(2)反复要求进行实验窒相关检查验证,怀疑或坚信感染HIV,影响正常工作与生活;(3)临床主诉繁多,主诉症状多以头痛、咽痛等流感样症状(15例)及肌肉震颤、皮肤蚁走感、关节疼痛(12例)、乏力(12例)、发热(但测量体温正常,12例)为主,体检除舌苔发白厚腻外未见明显阳性体征;(4)症状大多出现在高危行为后的0～3个月,期间重复HIV抗体检测呈阴性;(5)23例患者进行了T淋巴细胞哑群的检测,其中19例(82.6%)CD4+T淋巴细胞计数大于50个/μl,其余4例患者在300～500个/μl,最低者307个/μl,个别有CD4+/CD8+T淋巴细胞比例倒置情况,但CD8+T淋巴细胞均无异常激活表现.结论艾滋病恐惧症是一种复杂的躯体心理疾病,其诊断与治疗还需进一步探讨.
목적 총결애자병공구증환자림상특정,초보제출애자병공구증적림상진단의거.방법 수집애자병공구증환자림상자료,분석연구대상적일반인구학、림상표현급실험실검측결과.결과 애자병공구증환자림상특점포괄:(1)가존재혹불존재감염HIV적고위행위;(2)반복요구진행실험질상관검사험증,부의혹견신감염HIV,영향정상공작여생활;(3)림상주소번다,주소증상다이두통、인통등류감양증상(15례)급기육진전、피부의주감、관절동통(12례)、핍력(12례)、발열(단측량체온정상,12례)위주,체검제설태발백후니외미견명현양성체정;(4)증상대다출현재고위행위후적0～3개월,기간중복HIV항체검측정음성;(5)23례환자진행료T림파세포아군적검측,기중19례(82.6%)CD4+T림파세포계수대우50개/μl,기여4례환자재300～500개/μl,최저자307개/μl,개별유CD4+/CD8+T림파세포비례도치정황,단CD8+T림파세포균무이상격활표현.결론 애자병공구증시일충복잡적구체심리질병,기진단여치료환수진일보탐토.
objective To summarize the clinical characteristics of AIDS phobia patients and establish the preliminary clinical diagnostic criteria.Methods The clinical information of 46 AIDS phobia patients was collected and summarized.General demographic data,clinical manifestations and laboratory results were analyzed.Results The clinical characteristics of AIDS phobia patients include:(1)With or without high-risk behavior of HIV-1 infection;(2)Patients repeatedly demanded HIV/AIDS related laboratory tests,suspected or believed in HIV-1 infection with daily life affected;(3)The main complaints were non-specific including influenza-like symptoms(headache,sore throat and so on),fasciculation,formication,arthrodynia,fatigue and complaint of fever with normal body temperature;physical examination did not reveal any positive physical sign except white coated tongue;(4)Symptoms mainly appeared 0-3 months after the high-risk behavior while HIV-1 antibody kept negative;(5)T lymphocyte subsets test was carried out in 23 patients and showed 19(82.6%)with CD4+ T lymphocyte count>500/μl,the remaining 4 were 300-500/μl,with the lowest count of 307/μl.Few patients had inversed CD4+/CD8+ ratio but without excessive CD8+T lymphocyte activation.Conclusion AIDS phobia is a complicated physical and mental disease,whose diagnosis and treatment still need further investigation.