CAJ | 학술논문

目的观察分析接种国产甲型H1N1流感疫苗者的安全性.方法按照集中自愿的原则,对我院3 300例医务工作者接种上海生物制品有限公司生产、批号为200909012的甲型H1N1流感疫苗,并观察其接种后不良反应,包括接种半小时内、3天内和1周内不良反应例数及表现症状.结果 3 300例接种H1N1流感疫苗者中,有自觉不适或全身不良反应者占1.18%(39/3 300).接种疫苗后半小时内出现不适者占0.15%(5/3 300)接种疫苗后1～3天后出现不适者占0.70%(23/3 300);接种疫苗后3天至1周内出现不适者占0.33%(11/3 300).无严重不良反应发生.结论国产甲型H1N1流感疫苗不良反应发生较少,其安全性可靠,是目前预防甲型H1N1较经济有效的手段之一.
목적 관찰분석접충국산갑형H1N1류감역묘자적안전성.방법 안조집중자원적원칙,대아원3 300례의무공작자접충상해생물제품유한공사생산、비호위200909012적갑형H1N1류감역묘,병관찰기접충후불량반응,포괄접충반소시내、3천내화1주내불량반응례수급표현증상.결과 3 300례접충H1N1류감역묘자중,유자각불괄혹전신불량반응자점1.18%(39/3 300).접충역묘후반소시내출현불괄자점0.15%(5/3 300)접충역묘후1～3천후출현불괄자점0.70%(23/3 300);접충역묘후3천지1주내출현불괄자점0.33%(11/3 300).무엄중불량반응발생.결론 국산갑형H1N1류감역묘불량반응발생교소,기안전성가고,시목전예방갑형H1N1교경제유효적수단지일.
Objective To investigate safety of influenza A H1N1 vaccine vaccinations.Methods A total of 3 300 medical workers were vaccinated by batch of 200909012 influenza A H1N1 vaccine produced by Shanghai Biological Products Corporation Limited according to the principle of voluntary and concentration.The adverse reactions were observed within half an hour,three days and a week after vaccinations,respectively.Results The inoculators with local or systemic reaction reached 1.18% (39/3 300).There were 0.15% (5/3 300) of the inoculators with adverse reaction within half an hour;0.70% (23/3 300) within 1 to 3 days after vaccination;and 0.33% (11/3 300) within 3 days to 1 week after vaccination.No severe adverse events were found.Conclusion Influenza A H1N1 vaccine vaccinations is an economic and effective way of influenza A H1N1 prevention with mild reactions.