CAJ | 학술논문

目的探讨非心脏手术患者术后早期谵妄(EPD)与预后的关系.方法采用前瞻性队列研究设计,选择2009年6月至12月在本院全麻下行非心脏手术患者698例,收集影响患者预后的相关因素,根据CAM-ICU诊断标准判断是否发生EPD,分为EPD组和非EPD组(NEPD组),以术后住院时间作为主要预后指标,将EPD和对术后住院时间有影响的混杂因素纳入Cox比例风险回归模型进行分析,筛选影响患者预后的危险因素.结果 EPD组197例,NEPD组501例,EPD发生率28.2%,EPD组患者术后住院时间长于NEPD组,EPD是影响患者预后的独立危险因素之一.结论 EPD是影响非心脏手术患者预后的独立危因素之一.
목적 탐토비심장수술환자술후조기섬망(EPD)여예후적관계.방법 채용전첨성대렬연구설계,선택2009년6월지12월재본원전마하행비심장수술환자698례,수집영향환자예후적상관인소,근거CAM-ICU진단표준판단시부발생EPD,분위EPD조화비EPD조(NEPD조),이술후주원시간작위주요예후지표,장EPD화대술후주원시간유영향적혼잡인소납입Cox비례풍험회귀모형진행분석,사선영향환자예후적위험인소.결과 EPD조197례,NEPD조501례,EPD발생솔28.2%,EPD조환자술후주원시간장우NEPD조,EPD시영향환자예후적독립위험인소지일.결론 EPD시영향비심장수술환자예후적독립위인소지일.
Objective To determine the relationship between early postoperative delirium (EPD) and prognosis in patients undergoing non-cardiac surgery. Methods This was a prospective cohort study consisted of 698 patients admitted to postanesthesia care unit, undergoing non-cardiac surgery under general anesthesia, between June and December 2009. The risk factors affecting prognosis were collected. All the patients were assessed for the development of delirium by experienced research staff using Confusion Assessment Method for Intensive Care Unit. The patients were divided into 2 groups according to the occurrence of EPD: EPD group and no EPD (NEPD) group. The postoperative hospital length of stay was made as a major prognostic indicator. Cox proportional hazard regression model was used to analyze the risk factors affecting prognosis. Results Of the 698 patients, 197 (28.2%) developed EPD. The postoperative hospital length of stay was prolonged in group EPD compared with group NEPD. The Cox proportional hazard regression model analysis indicated that EPD was an independent risk factor affecting prognosis. Conclusion EPD is an independent risk factor affecting prognosis in patients undergoing non-cardiac surgery.