布地奈德/福莫特罗治疗哮喘为期三个月的非干预性调研
포지내덕/복막특라치료효천위기삼개월적비간예성조연
A Three-Month Non-Interventional Study of Asthma Treatment with Budesonide/Formoterol
  • 万方数据
    中国呼吸与危重监护杂志 중국호흡여위중감호잡지
    CHINESE JOURANL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    2009年 4期 341-344 ,共4页

    周新%洪建国%辛建保%吴昌归%薄建萍%张天托%王长征%蔡绍曦%刘纯%邱晨%黄建安%赖国祥%孔灵菲%刘春涛%马壮%黄克武%杨和平%周建英%陈卓昌%孙培宗%孙耕耘%王立波%唐素萍%陈志敏%李昌崇%赵德育%林荣军%郑跃杰%向莉%周小勤%陈育智

    주신%홍건국%신건보%오창귀%박건평%장천탁%왕장정%채소희%류순%구신%황건안%뢰국상%공령비%류춘도%마장%황극무%양화평%주건영%진탁창%손배종%손경운%왕립파%당소평%진지민%리창숭%조덕육%림영군%정약걸%향리%주소근%진육지

    布地奈德/福莫特罗%哮喘%治疗 佈地奈德/福莫特囉%哮喘%治療
    포지내덕/복막특라%효천%치료
    Budesonide/formoterol%Asthma%Therapy
    目的 评价和调查布地奈德/福莫特罗常规临床治疗哮喘的疗效和使用情况.方法 开展多中心、开放的、非干预性调查研究,观察哮喘患者使用布地奈德/福莫特罗治疗12周后的哮喘控制情况,以哮喘控制调查问卷(ACQ)与改良的哮喘控制调查问卷(ACQ5)平均分值为主要疗效观察指标.结果 共入选受试者360例,其中成人哮喘228例,儿童哮喘132例.经12周治疗后,所有患者ACQ平均分值由治疗前的2.03(成人2.20,儿童1.74)下降为0.60(成人0.78,儿童0.29),ACQ5平均分值由治疗前2.47(成人2.24,儿童1.76)下降为0.47(成人0.62,儿童0.20),差异均有统计学意义(P<0.0001).结论 布地奈德/福莫特罗在常规临床应用时可以有效地改善哮喘,并达到哮喘的良好临床控制.
    목적 평개화조사포지내덕/복막특라상규림상치료효천적료효화사용정황.방법 개전다중심、개방적、비간예성조사연구,관찰효천환자사용포지내덕/복막특라치료12주후적효천공제정황,이효천공제조사문권(ACQ)여개량적효천공제조사문권(ACQ5)평균분치위주요료효관찰지표.결과 공입선수시자360례,기중성인효천228례,인동효천132례.경12주치료후,소유환자ACQ평균분치유치료전적2.03(성인2.20,인동1.74)하강위0.60(성인0.78,인동0.29),ACQ5평균분치유치료전2.47(성인2.24,인동1.76)하강위0.47(성인0.62,인동0.20),차이균유통계학의의(P<0.0001).결론 포지내덕/복막특라재상규림상응용시가이유효지개선효천,병체도효천적량호림상공제.
    Objective To evaluate the efficacy of Budesonide/formoterol to control asthma under real-life conditions.Methods A muhi-center, open label, non-interventional study was conducted.Asthma control after 12 week therapy with Budesonide/formoterol was assessed by Asthma Control Questionnaire (ACQ) and modified Asthma Control Questionnaire (ACQ5).Results A total of 360 asthma patients were recruited,including 228 adult patients and 132 child patients.After 12 weeks' therapy,all the patients' medium value of ACQ was decreased significantly from 2.03 (adults 2.20, children 1.74) at baseline to 0.60 (adults 0.78, children 0.29) (P < 0.0001), and the medium value of ACQ5 was also decreased significantly from 2.4 (adults 2.24, children 1.76) at baseline to 0.47 (adults 0.62, children 0.20) (P < 0.0001).Conclusion Budesonide/formoterol is effective in asthma treatment, by which most asthma patients obtain and maintain clineal control.
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