国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2011年
11期
829-833
,共5页
姜贻乾%黄常新%李朝阳%段广亮
薑貽乾%黃常新%李朝暘%段廣亮
강이건%황상신%리조양%단엄량
热休克蛋白质类%抗原,肿瘤
熱休剋蛋白質類%抗原,腫瘤
열휴극단백질류%항원,종류
Heat-shock proteins%Antigens,neoplasms
伴侣分子抗原肽瘤苗因其化学性质稳定、易于制备、无潜在致癌性等优点,受到广泛关注.伴侣分子抗原肽瘤苗可通过伴侣分子的抗原提呈、增强机体的非特异性抗肿瘤机制以及激活特异性肿瘤免疫机制等多种途径发挥作用,其抗肿瘤机制的多样性等优点在肿瘤的临床免疫治疗中将有着积极的作用.
伴侶分子抗原肽瘤苗因其化學性質穩定、易于製備、無潛在緻癌性等優點,受到廣汎關註.伴侶分子抗原肽瘤苗可通過伴侶分子的抗原提呈、增彊機體的非特異性抗腫瘤機製以及激活特異性腫瘤免疫機製等多種途徑髮揮作用,其抗腫瘤機製的多樣性等優點在腫瘤的臨床免疫治療中將有著積極的作用.
반려분자항원태류묘인기화학성질은정、역우제비、무잠재치암성등우점,수도엄범관주.반려분자항원태류묘가통과반려분자적항원제정、증강궤체적비특이성항종류궤제이급격활특이성종류면역궤제등다충도경발휘작용,기항종류궤제적다양성등우점재종류적림상면역치료중장유착적겁적작용.
With the continuous development of tumor immunology,cancer vaccines have become a hot spot of tumor immunotherapy.Companion member antigen peptide tumor vaccine attracts widely attention because of its chemical stability,easy preparation and no carcinogenic potential advantage.Companion member antigen peptide tumor vaccine may work through many kinds of ways including the function of antigen presenting,enhancing the body's non-specific line of anti-tumor mechanisms and activating the tumor-specific immune mechanism.Its different anti-tumor mechanisms merits and so on will have positive function in the tumor clinical immunity treatment.