国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
3期
201-203
,共3页
孙士波%郝青林%徐鸥%罗壮%孙玉宝
孫士波%郝青林%徐鷗%囉壯%孫玉寶
손사파%학청림%서구%라장%손옥보
阻塞性睡眠呼吸暂停低通气综合征%自动调节压力持续正压通气%体质量指数%呼吸暂停低通气指数%微觉醒指数
阻塞性睡眠呼吸暫停低通氣綜閤徵%自動調節壓力持續正壓通氣%體質量指數%呼吸暫停低通氣指數%微覺醒指數
조새성수면호흡잠정저통기종합정%자동조절압력지속정압통기%체질량지수%호흡잠정저통기지수%미각성지수
Obstructive sleep apnea-hypopnea syndrome%Auto-continuous positive airway pressure%Body mass index%Apnea hypopnea index%Micro arousal index
目的 观察经过2年自动调节压力持续正压通气(AUTO-CPAP)治疗中、重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的患者体质量指数(BMI)的变化,停机后呼吸暂停低通气指数(AHI)、最低血氧饱和度( LSPO2)、微觉醒指数(MAI)、Ⅰ～Ⅱ期及Ⅲ～Ⅳ期睡眠时间占总睡眠时间百分比(Ⅰ～Ⅱ％,Ⅲ～Ⅳ％)的变化,探讨长期AUTO-CPAP呼吸机治疗对患者BMI的影响以及治疗后停机对患者的影响.方法 选取42例中、重度OSAHS患者,经AUTO -CPAP治疗2年、治疗时间≥5 h/d,治疗结束后对患者停机,并对患者行多导睡眠呼吸监测,观察治疗前后患者BMI、AHI、LSPO2、MAI、Ⅰ～Ⅱ％、Ⅲ～Ⅳ％的变化.结果 长期AUTO-CPAP治疗前后患者BMI无明显变化(P＞0.05),当治疗停止时,AHI从(43.6±12.6)次/h减少到(36.7±11.2)次/h,减少了(6.8±3.2)次/h(P＜0.01),LSPO2从(69.3±10.2)％上升到(76.4±8.1)％,升高了(7.1±2.6) ％(P ＜0.01),MAI从(38.1±12.2)次/h上升到(44.2±13.1)次/h,上升了(2.1±3.2)次/h( P＜0.01).Ⅰ～Ⅱ％,Ⅲ～Ⅳ％无明显变化(P＞0.05).结论 长期AUTO-CPAP治疗OSAHS对患者BMI无明显影响；有利于降低患者原有AHI、提高LSPO2；停机后对患者的影响主要表现在MAI的增加,而与Ⅰ～Ⅱ％、Ⅲ～Ⅳ％无关.
目的 觀察經過2年自動調節壓力持續正壓通氣(AUTO-CPAP)治療中、重度阻塞性睡眠呼吸暫停低通氣綜閤徵(OSAHS)的患者體質量指數(BMI)的變化,停機後呼吸暫停低通氣指數(AHI)、最低血氧飽和度( LSPO2)、微覺醒指數(MAI)、Ⅰ～Ⅱ期及Ⅲ～Ⅳ期睡眠時間佔總睡眠時間百分比(Ⅰ～Ⅱ％,Ⅲ～Ⅳ％)的變化,探討長期AUTO-CPAP呼吸機治療對患者BMI的影響以及治療後停機對患者的影響.方法 選取42例中、重度OSAHS患者,經AUTO -CPAP治療2年、治療時間≥5 h/d,治療結束後對患者停機,併對患者行多導睡眠呼吸鑑測,觀察治療前後患者BMI、AHI、LSPO2、MAI、Ⅰ～Ⅱ％、Ⅲ～Ⅳ％的變化.結果 長期AUTO-CPAP治療前後患者BMI無明顯變化(P＞0.05),噹治療停止時,AHI從(43.6±12.6)次/h減少到(36.7±11.2)次/h,減少瞭(6.8±3.2)次/h(P＜0.01),LSPO2從(69.3±10.2)％上升到(76.4±8.1)％,升高瞭(7.1±2.6) ％(P ＜0.01),MAI從(38.1±12.2)次/h上升到(44.2±13.1)次/h,上升瞭(2.1±3.2)次/h( P＜0.01).Ⅰ～Ⅱ％,Ⅲ～Ⅳ％無明顯變化(P＞0.05).結論 長期AUTO-CPAP治療OSAHS對患者BMI無明顯影響；有利于降低患者原有AHI、提高LSPO2；停機後對患者的影響主要錶現在MAI的增加,而與Ⅰ～Ⅱ％、Ⅲ～Ⅳ％無關.
목적 관찰경과2년자동조절압력지속정압통기(AUTO-CPAP)치료중、중도조새성수면호흡잠정저통기종합정(OSAHS)적환자체질량지수(BMI)적변화,정궤후호흡잠정저통기지수(AHI)、최저혈양포화도( LSPO2)、미각성지수(MAI)、Ⅰ～Ⅱ기급Ⅲ～Ⅳ기수면시간점총수면시간백분비(Ⅰ～Ⅱ％,Ⅲ～Ⅳ％)적변화,탐토장기AUTO-CPAP호흡궤치료대환자BMI적영향이급치료후정궤대환자적영향.방법 선취42례중、중도OSAHS환자,경AUTO -CPAP치료2년、치료시간≥5 h/d,치료결속후대환자정궤,병대환자행다도수면호흡감측,관찰치료전후환자BMI、AHI、LSPO2、MAI、Ⅰ～Ⅱ％、Ⅲ～Ⅳ％적변화.결과 장기AUTO-CPAP치료전후환자BMI무명현변화(P＞0.05),당치료정지시,AHI종(43.6±12.6)차/h감소도(36.7±11.2)차/h,감소료(6.8±3.2)차/h(P＜0.01),LSPO2종(69.3±10.2)％상승도(76.4±8.1)％,승고료(7.1±2.6) ％(P ＜0.01),MAI종(38.1±12.2)차/h상승도(44.2±13.1)차/h,상승료(2.1±3.2)차/h( P＜0.01).Ⅰ～Ⅱ％,Ⅲ～Ⅳ％무명현변화(P＞0.05).결론 장기AUTO-CPAP치료OSAHS대환자BMI무명현영향；유리우강저환자원유AHI、제고LSPO2；정궤후대환자적영향주요표현재MAI적증가,이여Ⅰ～Ⅱ％、Ⅲ～Ⅳ％무관.
Objective To observe the changement of body mass index (BMI),apnea hypopnea index (AHI),lowest pulse oxygen saturation (LSPO2),micro-arousal index (MAI),percentage of sleep Ⅰ ～ Ⅱ stage time and Ⅲ ～ Ⅳ stage time in the total time ( Ⅰ ～ Ⅱ％,Ⅲ ～ Ⅳ ％) in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) who had been treated with auto-continuous positive airway pressure (AUTO-CPAP) for two years.Methods The 42 patients who were diagnosized OSAHS with polysomnography (PSG) had been treated with AUTO-CPAP for two years,and the treatment time was not less than 5 hours pre day.The second PSG was taken in this patients after a two-years treatment.To observe the changement of the BMI,AHI,LSPO2,MAI,Ⅰ ～ Ⅱ ％,Ⅲ ～ Ⅳ ％ from pre-treatment to post-treatment.Results The BMI showed no difference between pre-treatment and post-treatment ( P ＞0.05).When the treatment being quitted,AHI reduced (6.8±3.2) times/h from (43.6±12.6) times/h to (36.7±11.2) times/h (P ＜0.05).And LSPO2 raised (7.1±2.6)％ from (69.3±10.2)％ to (76.4±8.1)％ (P ＜0.05).The MAI raised (2.1±3.2) times/h from (38.1±12.2) times/h to (44.2± 13.1) times/h ( P ＜0.05).And Ⅰ ～ Ⅱ ％,Ⅲ ～ Ⅳ ％ shows no difference between pre treatment and post-treatment ( P ＞0.05).Conclusions A long term treatment with AUTO-CPAP shows likely no influence to the BMI of the patients with OSHAS.A long term treatment with AUTO-CPAP is maybe benefit to the AHI and LSPO2.When the treatment being quitted,the influence to the patient not lies in Ⅰ ～ Ⅱ ％ or Ⅲ ～Ⅳ ％ but in the MAI.
