CAJ | 학술논문

目的观察三维适形放疗联合化疗及中药治疗中晚期食管癌的临床疗效.方法 36例中晚期食管癌患者,随机分为两组,对照组给予常规放、化疗,治疗组应用三维适形放疗联合化疗及中药治疗,比较两组患者的近期疗效、毒性反应及远期疗效,并对患者死亡原因进行分析.结果治疗组完全缓解率明显高于对照组(P＜0.05);毒性反应减低;两组患者1、3年生存率有显著性差异(P＜0.05),5年生存率无显著性差异(P＞0.05);局部未控制及复发率明显低于对照组(P＜0.05).结论采用三维适形放疗联合化疗及中药对中晚期食管癌的治疗效果优于常规放、化疗法.
목적 관찰삼유괄형방료연합화료급중약치료중만기식관암적림상료효.방법 36례중만기식관암환자,수궤분위량조,대조조급여상규방、화료,치료조응용삼유괄형방료연합화료급중약치료,비교량조환자적근기료효、독성반응급원기료효,병대환자사망원인진행분석.결과 치료조완전완해솔명현고우대조조(P＜0.05);독성반응감저;량조환자1、3년생존솔유현저성차이(P＜0.05),5년생존솔무현저성차이(P＞0.05);국부미공제급복발솔명현저우대조조(P＜0.05).결론 채용삼유괄형방료연합화료급중약대중만기식관암적치료효과우우상규방、화요법.
Objective To observe the clinical effect of treating advanced esophageal carcinoma with three-dimensional conformal radiotherapy combined with chemotherapy and traditional Chinese medicine.Methods 36 cases with advanced esophageal carcinoma were randomly divided into a eontrol group and a treatment group.The control group was treated with conventional radiotherapy combined with chemotherapy,and the treatment group was treated with three-dimensional conforrnal radiotherapy combined with chemotherapy and traditional Chinese medicine.The short-term effect,toxicity and long-term effect were observed,and cause of death was analyzed.Results The complete remission rate in the treatment group was significantly higher than that of the control group(P＜0.05).The toxicity of the treatment group was markedly decreased.One and three years'survival rate between the two groups had a significant difierent(P＜0.05),but five years'survival rate between the two groups had no significant difference(P＞0.05).Local uncontrolled rate and recurrence rate in the treatment group were significantly lower than those in the control group(p＜0.05).Conclusion The treatment of three-dimensional conformal radiotherapy combined with chemotherapy and traditional Chinese medicine on advanced esophageal carcinoma was better than conventional radiotherapy combined with chemotherapy.