中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
7期
920-922,后插5
,共4页
乙醇%腹腔丛%麻醉
乙醇%腹腔叢%痳醉
을순%복강총%마취
Ethanol%Celiac plexus%Anesthesia
目的 探讨麻醉状态下乙醇对腹腔神经丛毁损的作用.方法 选择36个择期行胰腺癌手术患者,ASA Ⅰ～Ⅲ,随机数字表法分为乙醇组与对照组,两组均给予丙泊酚(6～9 mg·kg～·d-1)和瑞芬太尼(0.1～0.3 μg·kg～·min-1)静脉麻醉,乙醇组对腹腔神经丛局部注射75%乙醇30 ml;对照组局部注射0.9%氯化钠注射液30 ml.分别记录注射前5 min、注射后1 min、5 min、15 min、25 min、35 min、45 min的脑电双频谱指数值(BIS值)、平均动脉压(MAP)、心率(HR).结果 与注射前相比:对照组各时点的BIS值与血流动力学值无明显变化,乙醇组注射后15 min至45 min四个时点BIS值、MAP明显下降,与对照组相同时点比较差异均有统计学意义(P＜0.001).结论 在丙泊酚瑞芬太尼麻醉下,术中使用乙醇能加深麻醉镇静深度.
目的 探討痳醉狀態下乙醇對腹腔神經叢燬損的作用.方法 選擇36箇擇期行胰腺癌手術患者,ASA Ⅰ～Ⅲ,隨機數字錶法分為乙醇組與對照組,兩組均給予丙泊酚(6～9 mg·kg～·d-1)和瑞芬太尼(0.1～0.3 μg·kg～·min-1)靜脈痳醉,乙醇組對腹腔神經叢跼部註射75%乙醇30 ml;對照組跼部註射0.9%氯化鈉註射液30 ml.分彆記錄註射前5 min、註射後1 min、5 min、15 min、25 min、35 min、45 min的腦電雙頻譜指數值(BIS值)、平均動脈壓(MAP)、心率(HR).結果 與註射前相比:對照組各時點的BIS值與血流動力學值無明顯變化,乙醇組註射後15 min至45 min四箇時點BIS值、MAP明顯下降,與對照組相同時點比較差異均有統計學意義(P＜0.001).結論 在丙泊酚瑞芬太尼痳醉下,術中使用乙醇能加深痳醉鎮靜深度.
목적 탐토마취상태하을순대복강신경총훼손적작용.방법 선택36개택기행이선암수술환자,ASA Ⅰ～Ⅲ,수궤수자표법분위을순조여대조조,량조균급여병박분(6～9 mg·kg～·d-1)화서분태니(0.1～0.3 μg·kg～·min-1)정맥마취,을순조대복강신경총국부주사75%을순30 ml;대조조국부주사0.9%록화납주사액30 ml.분별기록주사전5 min、주사후1 min、5 min、15 min、25 min、35 min、45 min적뇌전쌍빈보지수치(BIS치)、평균동맥압(MAP)、심솔(HR).결과 여주사전상비:대조조각시점적BIS치여혈류동역학치무명현변화,을순조주사후15 min지45 min사개시점BIS치、MAP명현하강,여대조조상동시점비교차이균유통계학의의(P＜0.001).결론 재병박분서분태니마취하,술중사용을순능가심마취진정심도.
Objective To investigate the effect of ethanol using by neurolytic celiac plexus block(NCPB)on the Bispectral index(BIS)during anaesthesia with propofol and remifentanil.Methods Thirty-six patients,ASA Ⅰ～Ⅲ,undergoing pancreatic cancer surgery were studied.Patients were maintained with propofol(6～9mg·kg～·h-1)and remifentanil(0.1～0.3μg·kg～·min-1)to keep the BIS between 38 and 50.After 30minutes of stable anesthesia,patients in control group were treated with NCPB by 0.9%NS 30ml,while patients in ethanol group were employed NCPB at the same time by 75%ethanol 30m1.BIS values,mean arterial pressure(MAP),heart rate(HR)were recorded 5minutes before the injection and one,five,fifteen,twenty five,thirty five,forty five minutes after that.Results Therewas no significant change in BIS,emodynamic variables compared to preinjection values in the control group.15min to 45min after injection of four point,BIS values and MAP of ethanol group decreased significantly,as compared with before injection,the same time point compared with the control group had statistically significant difference(P＜0.001).No significant changes in HR were observed throughout the observation.Conclusion Ethanol used in the operation of NCPB was additive to the anesthesia depth during the anesthesia of propofol and remifentanil.
