中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2010年
5期
391-395
,共5页
肿瘤残留或复发,鼻咽%体层摄影术,正电子发射,氟标记脱氧葡萄糖%磁共振成像
腫瘤殘留或複髮,鼻嚥%體層攝影術,正電子髮射,氟標記脫氧葡萄糖%磁共振成像
종류잔류혹복발,비인%체층섭영술,정전자발사,불표기탈양포도당%자공진성상
Neoplasm residue or recurrence,nasopharyngeal%Tomography,positron emissions,18F-labeled deoxyglucose%Magnetic resonance imaging
目的 比较氟标记脱氧葡萄糖(FDG)PET或PET-CT和MRI判断鼻咽癌放疗后局部残留或复发的价值.方法 检索Medline、Embase和Cochrane图书馆系统评价1995年1月至2009年8月相关FDG PET或PET-CT和MRI的原始文献.金标准为病理分析和(或)临床及影像学随访.2个人独立搜索文献和提取数据,分别计算出FDG PET或PET-CT与MRI的敏感性、特异性、汇总的受试者工作特征(SROC)曲线和Q*值.结果 17个FDG PET或PET-CT和10个MRI研究纳入分析,汇总的FDG PET或PET-CT与MRI的敏感性分别为0.935(95% CI=0.901～0.964)与0.792(95%CI=0.731～0.844),汇总的特异性分别为0.924(95% CI=0.898～0.945)与0.787(95% CI=0.746～0.825).PET或PET-CT的SROC曲线下面积明显大于MRI(0.966∶0.852;z=2.29,P<0.05).PET或PET-CT的Q*值明显高于MRI的(0.914∶0.783;z=2.94,P<0.05).结论 FDG PET或PET-CT在诊断鼻咽癌放疗后局部复发或残留的准确性高于MRI.
目的 比較氟標記脫氧葡萄糖(FDG)PET或PET-CT和MRI判斷鼻嚥癌放療後跼部殘留或複髮的價值.方法 檢索Medline、Embase和Cochrane圖書館繫統評價1995年1月至2009年8月相關FDG PET或PET-CT和MRI的原始文獻.金標準為病理分析和(或)臨床及影像學隨訪.2箇人獨立搜索文獻和提取數據,分彆計算齣FDG PET或PET-CT與MRI的敏感性、特異性、彙總的受試者工作特徵(SROC)麯線和Q*值.結果 17箇FDG PET或PET-CT和10箇MRI研究納入分析,彙總的FDG PET或PET-CT與MRI的敏感性分彆為0.935(95% CI=0.901～0.964)與0.792(95%CI=0.731～0.844),彙總的特異性分彆為0.924(95% CI=0.898～0.945)與0.787(95% CI=0.746～0.825).PET或PET-CT的SROC麯線下麵積明顯大于MRI(0.966∶0.852;z=2.29,P<0.05).PET或PET-CT的Q*值明顯高于MRI的(0.914∶0.783;z=2.94,P<0.05).結論 FDG PET或PET-CT在診斷鼻嚥癌放療後跼部複髮或殘留的準確性高于MRI.
목적 비교불표기탈양포도당(FDG)PET혹PET-CT화MRI판단비인암방료후국부잔류혹복발적개치.방법 검색Medline、Embase화Cochrane도서관계통평개1995년1월지2009년8월상관FDG PET혹PET-CT화MRI적원시문헌.금표준위병리분석화(혹)림상급영상학수방.2개인독립수색문헌화제취수거,분별계산출FDG PET혹PET-CT여MRI적민감성、특이성、회총적수시자공작특정(SROC)곡선화Q*치.결과 17개FDG PET혹PET-CT화10개MRI연구납입분석,회총적FDG PET혹PET-CT여MRI적민감성분별위0.935(95% CI=0.901～0.964)여0.792(95%CI=0.731～0.844),회총적특이성분별위0.924(95% CI=0.898～0.945)여0.787(95% CI=0.746～0.825).PET혹PET-CT적SROC곡선하면적명현대우MRI(0.966∶0.852;z=2.29,P<0.05).PET혹PET-CT적Q*치명현고우MRI적(0.914∶0.783;z=2.94,P<0.05).결론 FDG PET혹PET-CT재진단비인암방료후국부복발혹잔류적준학성고우MRI.
Objective To compare the value of 18 F-labeled deoxyglucose (FDG) PET or PET-CT with MRI in detecting local residue or recurrence of nasopharyngeal carcinoma after radiotherapy, by performing a meta-analysis of relevant trials.Methods A literature search was performed to English original articles about FDG PET or PET-CT and MRI in Medline, Embase and the Cochrane database from January 1995 to August 2009.The reference standard was histopathologic analysis and/or close clinical and imaging follow-up.Two reviewers searched articles and extracted data independently.Sensitivity, specificity,summary receiver operating characteristic curves (SROC), and the Q index for FDG PET or PET-CT and MRI were pooled, respectively.Results Seventeen studies about FDG PET or PET-CT and 10 studies about MRI were included in this meta-analysis.The pooled sensitivity of FDG PET or PET-CT and MRI were 0.935(95% CI= 0.901 -0.964) and 0.792 (95% CI= 0.731 -0.844), separately.The pooled specificity were 0.924 (95 % CI= 0.898 - 0.945) and 0.787 (95 % GI= 0.746 - 0.825), separately.Area under SROC curves of PET-CT or PET (0.966) was significantly larger than that of MRI (0.852) (z =2.29, P < 0.05).The Q * index estimates for PET-CT or PET (0.914) were significantly higher than for MRI (0.783)(z=2.94,P<0.05).Conclusions FDG-PET/PET-CT has higher accuracy than MRI in diagnosing local residue or recurrence of nasopharyngeal carcinoma after radiotherapy.
