CAJ | 학술논문

目的探讨内乳前哨淋巴结99Tcm-硫胶体(Sc)显像的影响因素,为提高显像效果提供依据.方法分析263例T1或T2期乳腺癌患者的内乳前哨淋巴结99Tcm-SC显像资料,选取患者年龄、肿块所在乳腺(左或右)、肿块所在象限、病灶性质、瘤周注射钟点位置、注射显像剂体积、显像剂放射性活度及显像延时时限共8个影响因素,用SPSS 11.5软件进行单因素和多因素分析,P<0.05为差异有统计学意义.结果左乳较右乳(Wald值为27.71,P<0.05)、内半乳腺较外半乳腺(Wald值为6.46,P=0.011)易出现内乳淋巴引流;瘤周3点注射法优于4点注射法(Wald值为11.57,P=0.001);每点0.5×10-3L 99Tcm-SC注射能取得较好的显像效果;在活度-体积组合中,活度不是关键性因素.年龄(Wald值为3.20,P=0.074)、病灶性质(Wald值为0.05,P=0.82)及显像延时时限(Wald值为0.69,P=0.41)对内乳前哨淋巴结显像无明显影响.结论在选取的8个因素中,肿块所在乳腺(左或右)、肿块所在象限、瘤周注射钟点位置、注射显像剂体积为影响内乳淋巴结显影的独立因素,年龄、病灶性质及延时时限与内乳前哨淋巴结显像无关.
목적 탐토내유전초림파결99Tcm-류효체(Sc)현상적영향인소,위제고현상효과제공의거.방법 분석263례T1혹T2기유선암환자적내유전초림파결99Tcm-SC현상자료,선취환자년령、종괴소재유선(좌혹우)、종괴소재상한、병조성질、류주주사종점위치、주사현상제체적、현상제방사성활도급현상연시시한공8개영향인소,용SPSS 11.5연건진행단인소화다인소분석,P<0.05위차이유통계학의의.결과 좌유교우유(Wald치위27.71,P<0.05)、내반유선교외반유선(Wald치위6.46,P=0.011)역출현내유림파인류;류주3점주사법우우4점주사법(Wald치위11.57,P=0.001);매점0.5×10-3L 99Tcm-SC주사능취득교호적현상효과;재활도-체적조합중,활도불시관건성인소.년령(Wald치위3.20,P=0.074)、병조성질(Wald치위0.05,P=0.82)급현상연시시한(Wald치위0.69,P=0.41)대내유전초림파결현상무명현영향.결론 재선취적8개인소중,종괴소재유선(좌혹우)、종괴소재상한、류주주사종점위치、주사현상제체적위영향내유림파결현영적독립인소,년령、병조성질급연시시한여내유전초림파결현상무관.
Objective The aim of this study was to investigate the possible influential factors in 99Tcm-sulphur colloid (SC) internal mammary sentinel node (IMSN) lymphoscintigraphy. Methods IMSN lymphoscintigraphy data from 263 breast cancer patients with T1 or T2 tumors were retrospectively reviewed. Parameters including patients'age, left or right breast, various quadrants, focus properties, o'clock site around tumor of injection, injection volume, injection radioactivity and delay time of imaging were selected as influential factors to be analyzed by single factor and multifactor analyses with SPSS 11.5, significant value was P<0.05. Results Left breast and inner half breast were easier to drain to internal mammary nodes (IMN) than that of right breast and outer haft breast (Wald=27.71, P<0.05 and Wald=6.46, P< 0.05). Peri-tumoral injection with three sites was better than with four sites (Wald=11.57, P=0.001). A better imaging quality was gained in 0.5×10-3 L per site. Radioactivity, age, location of injection, and delay time were insignificant to identify the IMSN. Conclusion Left breast and inner half breast, injection site, and injection volume are all independent factors affecting IMSN lymphoscintigraphy.