中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2012年
6期
526-528
,共3页
夏国金%龚洪翰%曾献军%姜建%周福庆%胡珍珍
夏國金%龔洪翰%曾獻軍%薑建%週福慶%鬍珍珍
하국금%공홍한%증헌군%강건%주복경%호진진
前列腺肿瘤%前列腺增生%磁共振成像
前列腺腫瘤%前列腺增生%磁共振成像
전렬선종류%전렬선증생%자공진성상
Prostatic neoplasms%Prostatic hyperplasia%Magnetic resonance imaging
目的 探讨MR DTI在前列腺癌诊断中的价值.方法 回顾性分析2009年10月至2010年12月期间,临床怀疑为前列腺癌且行MR常规检查及DTI扫描的44例患者的资料.病理证实为前列腺癌16例、良性前列腺增生28例.采用t检验比较前列腺癌、良性前列腺增生患者间各向异性分数(FA)值及ADC值的差异,采用ROC曲线分析FA值及ADC值对前列腺癌诊断效能,并初步确定前列腺癌FA值及ADC值诊断阈值.结果 前列腺癌区和良性前列腺增生的FA值分别为0.308±0.084和0.203±0.029,ADC值分别为(0.883±0.192)×10-3和( 1.408±0.130)×10-3mm2/s,差异均有统计学意义(￡值分别为4.833和10.779,P值均＜0.01).ROC曲线上,ADC曲线下面积为0.996(95％可信区间为0.984～1.007),FA值曲线下面积为0.904(95％可信区间为0.812～0.996),FA值联合ADC值的曲线下面积为0.996(95％可信区间为0.984～1.007).ADC值阈值为0.725×10-3mm2/s,敏感度为100.0％,特异度为96.0％；FA值阈值为0.311,敏感度为100.0％,特异度为68.7％.结论 DTI成像能为前列腺癌诊断及鉴别诊断提供有价值的信息,有助于提高对前列腺癌的诊断能力.
目的 探討MR DTI在前列腺癌診斷中的價值.方法 迴顧性分析2009年10月至2010年12月期間,臨床懷疑為前列腺癌且行MR常規檢查及DTI掃描的44例患者的資料.病理證實為前列腺癌16例、良性前列腺增生28例.採用t檢驗比較前列腺癌、良性前列腺增生患者間各嚮異性分數(FA)值及ADC值的差異,採用ROC麯線分析FA值及ADC值對前列腺癌診斷效能,併初步確定前列腺癌FA值及ADC值診斷閾值.結果 前列腺癌區和良性前列腺增生的FA值分彆為0.308±0.084和0.203±0.029,ADC值分彆為(0.883±0.192)×10-3和( 1.408±0.130)×10-3mm2/s,差異均有統計學意義(￡值分彆為4.833和10.779,P值均＜0.01).ROC麯線上,ADC麯線下麵積為0.996(95％可信區間為0.984～1.007),FA值麯線下麵積為0.904(95％可信區間為0.812～0.996),FA值聯閤ADC值的麯線下麵積為0.996(95％可信區間為0.984～1.007).ADC值閾值為0.725×10-3mm2/s,敏感度為100.0％,特異度為96.0％；FA值閾值為0.311,敏感度為100.0％,特異度為68.7％.結論 DTI成像能為前列腺癌診斷及鑒彆診斷提供有價值的信息,有助于提高對前列腺癌的診斷能力.
목적 탐토MR DTI재전렬선암진단중적개치.방법 회고성분석2009년10월지2010년12월기간,림상부의위전렬선암차행MR상규검사급DTI소묘적44례환자적자료.병리증실위전렬선암16례、량성전렬선증생28례.채용t검험비교전렬선암、량성전렬선증생환자간각향이성분수(FA)치급ADC치적차이,채용ROC곡선분석FA치급ADC치대전렬선암진단효능,병초보학정전렬선암FA치급ADC치진단역치.결과 전렬선암구화량성전렬선증생적FA치분별위0.308±0.084화0.203±0.029,ADC치분별위(0.883±0.192)×10-3화( 1.408±0.130)×10-3mm2/s,차이균유통계학의의(￡치분별위4.833화10.779,P치균＜0.01).ROC곡선상,ADC곡선하면적위0.996(95％가신구간위0.984～1.007),FA치곡선하면적위0.904(95％가신구간위0.812～0.996),FA치연합ADC치적곡선하면적위0.996(95％가신구간위0.984～1.007).ADC치역치위0.725×10-3mm2/s,민감도위100.0％,특이도위96.0％；FA치역치위0.311,민감도위100.0％,특이도위68.7％.결론 DTI성상능위전렬선암진단급감별진단제공유개치적신식,유조우제고대전렬선암적진단능력.
Objective To explore the diagnostic value of DTI for prostate cancer.Methods From October 2009 to December 2010,44 patients suspected of prostate cancer received MRI and DTI.The data of MRI and DTI were analyzed retrospectively.By histopathology,prostate cancer was proved in 16 patients,and benign prostatic hyperplasia ( BPH ) was proved in 28 patients.Differences in ADC and FA values between prostate cancer and BPH were compared by independent samples t test.Diagnostic accuracy of FA value and ADC value for prostate cancer was analyzed by using ROC curve,and the diagnostic threshold of FA value and ADC value for prostate cancer was determined.Results The mean FA value of the tumor regions and BPH were 0.308 +0.084 and 0.203 ±0.029,respectively.The mean ADC value of the tumor regions and BPH were (0.883 +0.192) × 10 -3 mm2/s and ( 1.408 ±0.130) × 10-3 mm2/s,respectively.There were statistically significant differences in ADC and FA values between tumor regions and BPH (t values were 4.833 and 10.779 respectively,P＜0.01).The ADC value area under curve of ROC was 0.996 (95％ CI was 0.984 to 1.007) ; the FA value area under curve of ROC was 0.904(95％ CI was 0.812 to 0.996) ; Combined the FA and ADC value area under curve of ROC is 0.996(95％ CI was 0.984to 1.007) ; Using the ADC value of 0.725 × 10 3 mm2/s as the ROC cut off point,the diagnostic sensitivity and specificity were 100.0％ and 96.0％,respectively; Using the FA value of 0.311as the ROC cut off point,the diagnostic sensitivity and specificity was 100.0％ and 68.7％,respectively.Conclusion DTI imaging can provide valuable information for prostate cancer diagnosis and differential diagnosis,and improve the diagnosis ability of prostate cancer.
