CAJ | 학술논문

目的探讨在保留膀胱的前提下对浸润性膀胱癌进行综合治疗的疗效.方法对74例不同分期、分级的浸润性膀胱癌患者随机分为两组,Ⅰ组42例行根治性膀胱切除术.Ⅱ组32例术前行卡铂配伍阿霉素髂内动脉灌注化疗两次,后行膀胱部分切除术或经尿道膀胱肿瘤电切术(TUR-Bt),术后加丝裂霉素膀胱灌注化疗.均随诊5年,比较两组间治疗后患者存活率.结果 Ⅰ组,5年存活率61.9%.Ⅱ组,5年存活率56.3%.两组存活率间比较差异无显著性(P>0.05).结论保留膀胱的前提下综合治疗浸润性膀胱癌是治疗浸润性膀胱癌的有效方法.
목적 탐토재보류방광적전제하대침윤성방광암진행종합치료적료효.방법 대74례불동분기、분급적침윤성방광암환자수궤분위량조,Ⅰ조42례행근치성방광절제술.Ⅱ조32례술전행잡박배오아매소가내동맥관주화료량차,후행방광부분절제술혹경뇨도방광종류전절술(TUR-Bt),술후가사렬매소방광관주화료.균수진5년,비교량조간치료후환자존활솔.결과 Ⅰ조,5년존활솔61.9%.Ⅱ조,5년존활솔56.3%.량조존활솔간비교차이무현저성(P>0.05).결론 보류방광적전제하종합치료침윤성방광암시치료침윤성방광암적유효방법.
Objective To evaluate the clinical effect of the combined therapy with bladder preservation for patients with invasive bladder cancer. Methods 74 cases of invasive bladder cancer patients of different sta-ges and grades were divided into two groups randomly. The 42 patients of control group received radical bladder cystectomy, while the 32 patients of the combined therapy group implemented twice intra-artery infusion chemo-therapy before the operation of partial cystectomy or TUR-Bt and bladder infusion chemotherapy postoperatively. All the patients were followed up for 5 years, and the survival rate of the two groups was compared. Results The 5 years survival rate were 61.9% and 56.3% in the control group and the combined therapy group respectively, there was no significant difference between the two groups (P>0.05). Conclusion The combined therapy with bladder preservation for invasive bladder cancer was an effective way to cure invasive bladder cancer.