中华麻醉学杂志
中華痳醉學雜誌
중화마취학잡지
CHINESE JOURNAL OF ANESTHESIOLOGY
2010年
9期
1142-1143
,共2页
投药,局部%注射,静脉内%硝酸甘油%剖宫产术%子宫收缩
投藥,跼部%註射,靜脈內%硝痠甘油%剖宮產術%子宮收縮
투약,국부%주사,정맥내%초산감유%부궁산술%자궁수축
Administration,topical%Injections,intravenous%Nitroglycerin%Cesarean section%Uterine contraction
目的 比较剖宫产术患者局部注射与静脉注射硝酸甘油的子宫松弛效应.方法 拟行剖宫产术患者60例,年龄25～35岁,ASA分级Ⅰ级,体重60～90kg,随机分为3组(n=20),对照组(C组),静脉注射组(Ⅰ组)分离子宫后静脉注射硝酸甘油0.2 mg,局部注射组(L组)分离子宫后局部注射硝酸甘油0.2 mg.记录胎儿娩出时间、术中出血量,于切子宫、切子宫后3、5、10、15、20 min时记录MAP.结果 与C组比较,Ⅰ组和L组切子宫时MAP降低,胎儿娩出时间缩短,Ⅰ组术中出血量增加,L组术中出血量减少(P＜0.05);与Ⅰ组比较,Ⅱ组切子宫、切子宫后3、5、10 min时MAP升高,胎儿娩出时间缩短,术中出血量减少(P＜0.05).结论 剖宫产术患者子宫局部注射硝酸甘油产生的子宫松弛效应优于静脉注射.
目的 比較剖宮產術患者跼部註射與靜脈註射硝痠甘油的子宮鬆弛效應.方法 擬行剖宮產術患者60例,年齡25～35歲,ASA分級Ⅰ級,體重60～90kg,隨機分為3組(n=20),對照組(C組),靜脈註射組(Ⅰ組)分離子宮後靜脈註射硝痠甘油0.2 mg,跼部註射組(L組)分離子宮後跼部註射硝痠甘油0.2 mg.記錄胎兒娩齣時間、術中齣血量,于切子宮、切子宮後3、5、10、15、20 min時記錄MAP.結果 與C組比較,Ⅰ組和L組切子宮時MAP降低,胎兒娩齣時間縮短,Ⅰ組術中齣血量增加,L組術中齣血量減少(P＜0.05);與Ⅰ組比較,Ⅱ組切子宮、切子宮後3、5、10 min時MAP升高,胎兒娩齣時間縮短,術中齣血量減少(P＜0.05).結論 剖宮產術患者子宮跼部註射硝痠甘油產生的子宮鬆弛效應優于靜脈註射.
목적 비교부궁산술환자국부주사여정맥주사초산감유적자궁송이효응.방법 의행부궁산술환자60례,년령25～35세,ASA분급Ⅰ급,체중60～90kg,수궤분위3조(n=20),대조조(C조),정맥주사조(Ⅰ조)분리자궁후정맥주사초산감유0.2 mg,국부주사조(L조)분리자궁후국부주사초산감유0.2 mg.기록태인면출시간、술중출혈량,우절자궁、절자궁후3、5、10、15、20 min시기록MAP.결과 여C조비교,Ⅰ조화L조절자궁시MAP강저,태인면출시간축단,Ⅰ조술중출혈량증가,L조술중출혈량감소(P＜0.05);여Ⅰ조비교,Ⅱ조절자궁、절자궁후3、5、10 min시MAP승고,태인면출시간축단,술중출혈량감소(P＜0.05).결론 부궁산술환자자궁국부주사초산감유산생적자궁송이효응우우정맥주사.
Objective To compare the efficacy of nitroglycerine administered by local application and intravenous injection for uterine relaxation in patients undergoing caesarean section. Methods Sixty ASA Ⅰ patients, aged 25-35 yr, weighing 60-90 kg, undergoing caesarean section, were randomly allocated into 3 groups ( n = 20 each): control group (group C), intravenous injection group (group I) and local application group (group L). Combined spinal-epidural block was used in the patients. After isolation of uterus, nitroglycerine 0.2 mg was injected intravenously in group Ⅰ and was injected into uterine muscle in group L. The delivery time, blood loss during operation and MAP at the time of uterus incision and 3, 5, 10, 15 and 20 min after uterus incision were recorded. Results Compared with group C, MAP at the time of uterus incision was significantly decreased and the delivery time was significantly shortened in group Ⅰ and L, and the blood loss during operation was significantly increased in group Ⅰ while decreased in group L ( P ＜ 0.05). MAP at the time of uterus incision and 3, 5, and 10 min after uterus incision was significantly increased, the delivery time was significantly shortened, and the blood loss during operation was significantly decreased in group L compared with group Ⅰ ( P ＜ 0.05). Conclusion Local application of nitroglycerine exerts better efficacy than intravenous injection for uterine relaxation in patients undergoing caesarean section.
