上海交通大学学报（医学版）
上海交通大學學報（醫學版）
상해교통대학학보（의학판）
JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY(MEDICAL SCIENCE)
2010年
2期
143-146
,共4页
食物不耐受%过敏原特异性IgG%过敏性疾病
食物不耐受%過敏原特異性IgG%過敏性疾病
식물불내수%과민원특이성IgG%과민성질병
food intolerance%allergen-specific IgG%allergic disease
目的 探讨14种食物过敏原特异性IgG检测的临床意义.方法 采用酶联免疫吸附法检测211例过敏性疾病患者血清中14种食物过敏原特异性IgG,并在不同年龄段、不同性别、不同疾病患者间比较各种食物IgG阳性率.结果 211例患者中,食物过敏原特异性IgG阳性者193例(91.4%).14种食物中,鸡蛋的特异性IgG阳性率(73.9%)最高,其次为牛奶(70.6%);未见鸡肉和猪肉的特异性IgG升高.0-12个月年龄组患者以牛奶为首要过敏原,其余年龄组均以鸡蛋为首要过敏原.牛奶特异性IgG阳性率在各年龄组间比较,差异有统计学意义(P<0.01).食物过敏原特异性IgG阳性率在男女患者间比较,差异无统计学意义(P>0.05).湿疹患者食物过敏原特异性IgG阳性率(96.4%)最高,慢性腹泻患者阳性率(83.3%)最低;但各种疾病间比较,差异无统计学意义(P>0.05);牛奶特异性IgG阳性率在各种疾病间比较,差异有统计学意义(P<0.01);过敏性紫癜患者对12种过敏原(鸡肉和猪肉除外)均显示阳性反应.结论 食物不耐受是一种复杂的变态反应,血清食物过敏原特异性IgG的检测对过敏性疾病的病因诊断具有重要的指导意义.
目的 探討14種食物過敏原特異性IgG檢測的臨床意義.方法 採用酶聯免疫吸附法檢測211例過敏性疾病患者血清中14種食物過敏原特異性IgG,併在不同年齡段、不同性彆、不同疾病患者間比較各種食物IgG暘性率.結果 211例患者中,食物過敏原特異性IgG暘性者193例(91.4%).14種食物中,鷄蛋的特異性IgG暘性率(73.9%)最高,其次為牛奶(70.6%);未見鷄肉和豬肉的特異性IgG升高.0-12箇月年齡組患者以牛奶為首要過敏原,其餘年齡組均以鷄蛋為首要過敏原.牛奶特異性IgG暘性率在各年齡組間比較,差異有統計學意義(P<0.01).食物過敏原特異性IgG暘性率在男女患者間比較,差異無統計學意義(P>0.05).濕疹患者食物過敏原特異性IgG暘性率(96.4%)最高,慢性腹瀉患者暘性率(83.3%)最低;但各種疾病間比較,差異無統計學意義(P>0.05);牛奶特異性IgG暘性率在各種疾病間比較,差異有統計學意義(P<0.01);過敏性紫癜患者對12種過敏原(鷄肉和豬肉除外)均顯示暘性反應.結論 食物不耐受是一種複雜的變態反應,血清食物過敏原特異性IgG的檢測對過敏性疾病的病因診斷具有重要的指導意義.
목적 탐토14충식물과민원특이성IgG검측적림상의의.방법 채용매련면역흡부법검측211례과민성질병환자혈청중14충식물과민원특이성IgG,병재불동년령단、불동성별、불동질병환자간비교각충식물IgG양성솔.결과 211례환자중,식물과민원특이성IgG양성자193례(91.4%).14충식물중,계단적특이성IgG양성솔(73.9%)최고,기차위우내(70.6%);미견계육화저육적특이성IgG승고.0-12개월년령조환자이우내위수요과민원,기여년령조균이계단위수요과민원.우내특이성IgG양성솔재각년령조간비교,차이유통계학의의(P<0.01).식물과민원특이성IgG양성솔재남녀환자간비교,차이무통계학의의(P>0.05).습진환자식물과민원특이성IgG양성솔(96.4%)최고,만성복사환자양성솔(83.3%)최저;단각충질병간비교,차이무통계학의의(P>0.05);우내특이성IgG양성솔재각충질병간비교,차이유통계학의의(P<0.01);과민성자전환자대12충과민원(계육화저육제외)균현시양성반응.결론 식물불내수시일충복잡적변태반응,혈청식물과민원특이성IgG적검측대과민성질병적병인진단구유중요적지도의의.
Objective To explore the clinical significance of detection of 14 kinds of food allergen-specific IgG. Methods Fourteen kinds of food allergen-specific IgG were detected by ELISA method in 211 patients with allergic diseases,and IgG positive rates of various foods were compared among patients with different sex,age and allergic diseases. Results Positive food allergen-specific IgG was detected in 193(91.4%)patients.Among 14 kinds of foods,the positive rate of food allergen-specific IgG was the highest for eggs(73.9%),and milk came the second.However,no elevated food allergen-specific IgG was observed for chicken and meat.Milk was the most common sensitizers for 0-12 month-old patients,and egg was the first cause for the other age groups.There were significant differences in the positive rates of food allergen-specific IgG for milk among different age groups(P<0.01).There was no significant difference in the positive rate of food allergen-specific IgG between males and females(P>0.05).The positive rate of food allergen-specific IgG in patients with eczema was the highest(96.4%),and the lowest(83.3%)was found in those with chronic diarrhea,while there was no significant difference among different diseases(P>0.05).The positive rate of food allergen-specific IgG for milk differed significantly among different diseases(P<0.01).Positive food allergen-specific IgG was detected in 12 kinds of food(except for chicken and meat) for patients with allergic purpura. Conclusion Food intolerance is a complex allergy.The food allergen-specific IgG detection is of great importance as reference for etiologic diagnosis of allergic diseases.
