CAJ | 학술논문

127例社区2型糖尿病患者分为低血糖指数膳食替代组(实验组)和普通膳食组(对照组),试验周期12周.结果显示,实验组空腹血糖、餐后2h血糖、空腹胰岛素、稳态模型评估的胰岛素抵抗指数水平较基线明显下降(P＜0.05或P＜0.01),而HbA1C、血脂水平差异无统计学意义.另外实验组体脂百分数、内脏脂肪面积、腰臀比也较实验前明显下降(均P＜0.01).实验组12周后其超氧化物歧化酶和谷胱甘肽水平均升高、丙二醛水平降低(均P＜0.01).上述指标在对照组均无明显变化.实验组与对照组的体重、体重指数和腰围均较实验前下降(P＜0.01),但实验后组间比较差异无统计学意义.
127례사구2형당뇨병환자분위저혈당지수선식체대조(실험조)화보통선식조(대조조),시험주기12주.결과현시,실험조공복혈당、찬후2h혈당、공복이도소、은태모형평고적이도소저항지수수평교기선명현하강(P＜0.05혹P＜0.01),이HbA1C、혈지수평차이무통계학의의.령외실험조체지백분수、내장지방면적、요둔비야교실험전명현하강(균P＜0.01).실험조12주후기초양화물기화매화곡광감태수평균승고、병이철수평강저(균P＜0.01).상술지표재대조조균무명현변화.실험조여대조조적체중、체중지수화요위균교실험전하강(P＜0.01),단실험후조간비교차이무통계학의의.
A total of 127 type 2 diabetic patients were divided into low glycemic index meal replacements (intervention) group and standard food-based diet (reference) group in an experiment for 12 weeks.The results showed that fasting plasma glucose,postprandial 2 h plasma glucose,fasting insulin,and homeostasis model assessment insulin resistance(HOMA-IR) in the intervention group decreased significantly after 12 weeks trial ( P＜0.05 or P＜0.01 ).However,there were no significant changes in lipid profile and HbA1C in intervention group.In addition,percentage of body fatty,visceral fatty area,and waist-hip ratio also decreased in intervention group( all P＜0.01 ).Superoxide dismutase and glutathione levels increased significantly in intervention group by the end of trial (both P＜0.01 ),while malondialdehyde was decreased (P＜0.01 ).There were no significant changes in the aforementioned indices in the reference group.Weight,body mass index,and waist circumferences were decreased in both groups,but without significant difference between the two groups.