CAJ | 학술논문

目的研究低熔点合金铅补偿器在临床调强放疗中的应用价值.方法用计划系统输出射野强度分布文件(Dicom RT),通过测定低熔点合金铅衰减因子计算出Dicom RT文件对应射野中每个像素对应的加工深度,产生用于AUTIMO 3D数控切割机的控制文件,然后使用加工好的泡沫浇铸低熔点合金铅成型,产生调强放疗所需补偿器并通过MatriXX的质量控制测试系统对其检测.同时随机对比了10例患者多叶准直器和低熔点合金铅补偿器调强放疗的测试结果.结果治疗中心点剂量和面剂量显示使用低熔点合金铅补偿器调强放疗能产生和计划系统基本相同的剂量分布,误差在5％以内且临床可接受.与多叶准直器相比,低熔点合金铅补偿器调强放疗所需放疗时间少[(4.44±0.39) min:(5.71±0.57) min (t=10.82,P=0.000)]、机器跳数少[(462.5±65.8)MU:(524.5±99.6) MU (t=3.14,P=0.012)].结论铅补偿调强放疗技术相比于MLC的独特优势在于临床上有重要推广价值,为广大基层医院在低成本条件下开展精确放疗提供了一套可行方法.
목적 연구저용점합금연보상기재림상조강방료중적응용개치.방법 용계화계통수출사야강도분포문건(Dicom RT),통과측정저용점합금연쇠감인자계산출Dicom RT문건대응사야중매개상소대응적가공심도,산생용우AUTIMO 3D수공절할궤적공제문건,연후사용가공호적포말요주저용점합금연성형,산생조강방료소수보상기병통과MatriXX적질량공제측시계통대기검측.동시수궤대비료10례환자다협준직기화저용점합금연보상기조강방료적측시결과.결과 치료중심점제량화면제량현시사용저용점합금연보상기조강방료능산생화계화계통기본상동적제량분포,오차재5％이내차림상가접수.여다협준직기상비,저용점합금연보상기조강방료소수방료시간소[(4.44±0.39) min:(5.71±0.57) min (t=10.82,P=0.000)]、궤기도수소[(462.5±65.8)MU:(524.5±99.6) MU (t=3.14,P=0.012)].결론 연보상조강방료기술상비우MLC적독특우세재우림상상유중요추엄개치,위엄대기층의원재저성본조건하개전정학방료제공료일투가행방법.
Objective To study the using of cerrobase as the compensation material in the intensitymodulated radiation therapy (IMRT) implementation and impact factors.Methods With therapy planning system (TPS) exported the radiation field intensity file (Dicom RT),through measuring the attenuation coefficient of cerrobase,to calculate the processing depth of AUTIMO 3D CNC corresponding for Dicom RT files at each pixel,then using the processed foam casting of Cerrobase,produced the required IMRT compensator.Through the MATRIXX testing the IMRT compensator in clinical implementation.At the same time we compared the MU of using multi-leaf collimator (MLC) and Cerrobase IMRT compensator for 10patients.Results With cerrobase compensation IMRT can get similar dose or dose distribution to dose produced by TPS for point or plane dose,error is within 5％.To comparison with MLC,using cerrobase compensator has fewer treatment times ( (4.44±0.39) min:(5.71±0.57) min (t =10.82,P =0.000) )and fewer MU (462.5 ± 65.8) MU:(524.5±99.6) MU(t=3.14,P=0.012) ).Conclusions Comparison with MLC IMRT,the cerrobase compensation technique has an important application value with its unique advantages.This research provides an implemented method of IMRT radiotherapy for the primaryhospital.