中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2012年
1期
31-33
,共3页
高阅春%玉献鹏%何继强%陈方
高閱春%玉獻鵬%何繼彊%陳方
고열춘%옥헌붕%하계강%진방
冠心病%血管成形术,经腔,经皮冠状动脉%SYNTAX积分
冠心病%血管成形術,經腔,經皮冠狀動脈%SYNTAX積分
관심병%혈관성형술,경강,경피관상동맥%SYNTAX적분
Coronary disease%Angioplasty,transluminal,percultaneous coronary%SYNTAX score
目的 研究SYNTAX积分对复杂冠心病患者经皮冠状动脉(冠脉)介入治疗术(PCI)效果预测作用.方法 回顾性分析PCI置入雷帕霉素药物洗脱支架左主干/3支病变的冠心病患者共190例,计算SYNTAX积分及临床SYNTAX积分,随访其主要不良心脑血管事件(MACCE),包括死亡、非致命性心肌梗死、再次血运重建、脑血管事件发生率.分别评价SYNTAX积分及临床SYNTAX 积分对PCI效果的预测作用.结果 SYNTAX积分低、中及高分组的MACCE率分别为9.1％、16.2％及30.9％.临床SYNTAX评分低、中及高分组的MACCE率分别为14.9％、9.8％及30.6％,单因素及多因素分析结果均显示SYNTAX积分及临床SYNTAX积分是MACCE的独立预测因子.ROC 曲线分析结果SYNTAX积分AUC (0.667)大于临床SYNTAX积分AUC (0.636).结论 SYNTAX积分及临床SYNTAX积分对冠脉左主干/3支病变患者行PCI治疗后是否发生MACCE均有预测作用,在这一组人群中临床SYNTAX积分不优于SYNTAX积分.
目的 研究SYNTAX積分對複雜冠心病患者經皮冠狀動脈(冠脈)介入治療術(PCI)效果預測作用.方法 迴顧性分析PCI置入雷帕黴素藥物洗脫支架左主榦/3支病變的冠心病患者共190例,計算SYNTAX積分及臨床SYNTAX積分,隨訪其主要不良心腦血管事件(MACCE),包括死亡、非緻命性心肌梗死、再次血運重建、腦血管事件髮生率.分彆評價SYNTAX積分及臨床SYNTAX 積分對PCI效果的預測作用.結果 SYNTAX積分低、中及高分組的MACCE率分彆為9.1％、16.2％及30.9％.臨床SYNTAX評分低、中及高分組的MACCE率分彆為14.9％、9.8％及30.6％,單因素及多因素分析結果均顯示SYNTAX積分及臨床SYNTAX積分是MACCE的獨立預測因子.ROC 麯線分析結果SYNTAX積分AUC (0.667)大于臨床SYNTAX積分AUC (0.636).結論 SYNTAX積分及臨床SYNTAX積分對冠脈左主榦/3支病變患者行PCI治療後是否髮生MACCE均有預測作用,在這一組人群中臨床SYNTAX積分不優于SYNTAX積分.
목적 연구SYNTAX적분대복잡관심병환자경피관상동맥(관맥)개입치료술(PCI)효과예측작용.방법 회고성분석PCI치입뢰파매소약물세탈지가좌주간/3지병변적관심병환자공190례,계산SYNTAX적분급림상SYNTAX적분,수방기주요불양심뇌혈관사건(MACCE),포괄사망、비치명성심기경사、재차혈운중건、뇌혈관사건발생솔.분별평개SYNTAX적분급림상SYNTAX 적분대PCI효과적예측작용.결과 SYNTAX적분저、중급고분조적MACCE솔분별위9.1％、16.2％급30.9％.림상SYNTAX평분저、중급고분조적MACCE솔분별위14.9％、9.8％급30.6％,단인소급다인소분석결과균현시SYNTAX적분급림상SYNTAX적분시MACCE적독립예측인자.ROC 곡선분석결과SYNTAX적분AUC (0.667)대우림상SYNTAX적분AUC (0.636).결론 SYNTAX적분급림상SYNTAX적분대관맥좌주간/3지병변환자행PCI치료후시부발생MACCE균유예측작용,재저일조인군중림상SYNTAX적분불우우SYNTAX적분.
Objective To assess the value of SYNTAX score to predict major adverse cardiac and cerebrovascular events (MACCE) among patients with three-vessel or left-main coronary artery disease undergoing percutaneous coronary intervention.Methods 190 patients with three-vessel or left-main coronary artery disease undergoing percutaneous coronary intervention (PCI) with Cypher select drug-eluting stent were enrolled.SYNTAX score and clinical SYNTAX score were retrospectively calculated.Our clinical Endpoint focused on MACCE,a composite of death,nonfatal myocardial infarction (MI),stroke and repeat revascularization.The value of SYNTAX score and clinical SYNTAX score to predict MACCE were studied respectively.Results 29 patients were observed to suffer from MACCE,accouting 18.5％ of the overall 190 patients.MACCE rates of low ( ≤ 20.5 ),intermediate ( 21.0-31.0 ),and high ( ≥ 31.5 ) tertiles according to SYNTAX score were 9.1％,16.2％ and 30.9％ respectively.Both univariate and multivariate analysis showed that SYNTAX score was the independent predictor of MACCE.MACCE rates of low ( ≤ 19.5 ),intermediate( 19.6-29.1 ),and high( ≥29.2) tertiles according to clinical SYNTAX score were 14.9％,9.8％ and 30.6％ respectively.Both univariate and multivariate analysis showed that clinical SYNTAX score was the independent predictor of MACCE.ROC analysis showed both SYNTAX score ( AUC =0.667,P =0.004) and clinical SYNTAX score ( AUC =0.636,P =0.020) had predictive value of MACCE.Clinical SYNTAX score failed to show better predictive ability than the SYNTAX score.Conclusions Both SYNTAX score and clinical SYNTAX score could be independent risk predictors for MACCE among patients with three-vessel or left-main coronary artery disease undergoing percutaneous coronary intervention.Clinical SYNTAX score failed to show better predictive ability than the SYNTAX score in this group of patients.
