CAJ | 학술논문

目的探讨超声引导下经皮空心针穿刺(CNB)组织病理学检查诊断乳腺病灶的临床价值.方法回顾性分析177例乳腺病灶的超声引导下CNB病理学检查结果 ,并与术后组织病理学诊断结果进行比较,评价CNB诊断的效果.结果 177例乳腺病灶组织中,CNB病理诊断乳腺痛129例,术后病理组织学诊断乳腺癌136例,CNB病理诊断假阴性7例.CNB病理诊断乳腺癌的灵敏度为94.9%,特异度为100%,准确率为96.0%,阳性预测值为100%,阴性预测值为85.4%,约登指数为0.949,Kappa值为0.895(P<0.01).结论 CNB组织病理诊断乳腺病灶具有较高的准确性,与术后病理组织学诊断结果一致性较高,是一种可靠的乳腺病灶活检方法 .
목적 탐토초성인도하경피공심침천자(CNB)조직병이학검사진단유선병조적림상개치.방법 회고성분석177례유선병조적초성인도하CNB병이학검사결과 ,병여술후조직병이학진단결과 진행비교,평개CNB진단적효과.결과 177례유선병조조직중,CNB병리진단유선통129례,술후병리조직학진단유선암136례,CNB병리진단가음성7례.CNB병리진단유선암적령민도위94.9%,특이도위100%,준학솔위96.0%,양성예측치위100%,음성예측치위85.4%,약등지수위0.949,Kappa치위0.895(P<0.01).결론 CNB조직병리진단유선병조구유교고적준학성,여술후병리조직학진단결과 일치성교고,시일충가고적유선병조활검방법 .
Objective To investigate the accuracy, consistency and related affecting factors in pathological results of breast lesions diagnosed by ultrasound-guided core needle biopsy ( CNB) and conventional excision histopathology. Methods The clinical data of 177 consecutive cases of breast lesions examined by ultrasound-guided CNB and subsequently excised were reviewed from Jan. 2003 to Nov. 2009.The agreement of pathological diagnosis between the CNB and subsequent excision pathology was analyzed. Results There were 136 cancers in the final diagnosis after surgical excision among 386 breast lesions and 129 of them were diagnosed by CNB. The sensitivity (true positive) of CNB was 94.9% , false negative rate was 5.1% , specificity (true negative) was 100% , false positive rate 0, Youden's index was 0. 949,and positive predictive value and negative predictive value were 100% and 85. 4% , respectively. Condensation rate was 96.0% and Kappa value was 0. 895.Conclusion Ultrasound-guided CNB with histopathological assessment is accurate in diagnosis of breast lesions and has a great consistency with conventional excision pathology. It is a reliable method for the diagnosis of breast lesions to avoid an over-reliance on excision pathological examination.