CAJ | 학술논문

背景:小脑具有语言加工功能,并且这种功能主要表现在小脑右侧,但这样的结论到目前为止还存在争议.此外,小脑左侧是否同样参与语言加工?目的:通过检测参与言语产生加工过程的相应激活脑区,观察右侧及左侧小脑在言语产生中的激活情况.设计、时间及地点:对照观察,于2008-06/07在广州中医药大学第一附属医院MR室完成.对象:8名健康的右利手大学生,无色盲或色弱等,均自愿参加实验.方法:实验采用组块设计,作业任务是动词产生,要求被试根据屏幕中间呈现的名词默念1个与呈现名词相关的动词;对照任务要求被试注视屏幕中间呈现的注视点"+". 同时实时功能核磁共振扫描,利用AFNI软件对功能数据进行划感兴趣区分析.主要观察指标:观察分析动词产生作业中小脑的激活位置、坐标、体积等统计数据和脑激活图.结果:动词产生激活了右侧小脑,同时左侧小脑也表现出明显的激活,且激活体积比右侧大.结论:小脑的语言功能不仅仅局限于右侧小脑,左侧小脑可能也参与了语言功能的加工.
배경:소뇌구유어언가공공능,병차저충공능주요표현재소뇌우측,단저양적결론도목전위지환존재쟁의.차외,소뇌좌측시부동양삼여어언가공?목적:통과검측삼여언어산생가공과정적상응격활뇌구,관찰우측급좌측소뇌재언어산생중적격활정황.설계、시간급지점:대조관찰,우2008-06/07재엄주중의약대학제일부속의원MR실완성.대상:8명건강적우리수대학생,무색맹혹색약등,균자원삼가실험.방법:실험채용조괴설계,작업임무시동사산생,요구피시근거병막중간정현적명사묵념1개여정현명사상관적동사;대조임무요구피시주시병막중간정현적주시점"+". 동시실시공능핵자공진소묘,이용AFNI연건대공능수거진행화감흥취구분석.주요관찰지표:관찰분석동사산생작업중소뇌적격활위치、좌표、체적등통계수거화뇌격활도.결과:동사산생격활료우측소뇌,동시좌측소뇌야표현출명현적격활,차격활체적비우측대.결론:소뇌적어언공능불부부국한우우측소뇌,좌측소뇌가능야삼여료어언공능적가공.
BACKGROUND: The right hemisphere of the cerebellum was involved in linguistic function was disputed. In addition,there was no research report which suggested that the left hemisphere of the cerebellum participated in language processing as same as the right hemisphere. OBJECTIVE: To explore the activation of fight cerebellar hemisphere involved in speech production as well as to discuss the role of left cerebellar hemisphere in speech by means of examining the activated brain regions related the processing of speech production. DESIGN,TIME AND SETTING: Comparison observation,performed at Department of Magnetic Resonance,the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine between June and July 2008.PARTICIPANTS: Eight normal undergraduate with right-handed but without achromatopsia or hypochromatopsia volunteered to participate in the study. METHODS: Block design was used in this study. Subjects were required to generate a verb related to the Chinese 2-word noun represented visually and the functional scans were performed at the same time,and then the functional data were dealt with analysis of functional neuroimages (AFNI) and analyzed by drawing region of interest (ROI).MAIN OUTCOME MEASURES: The activation location,coordinate,voxel and the brain activation picture. RESULTS: Verb generation not only activated the right cerebellar hemisphere,but also the left cerebellar hemisphere.And the volumes activated in the left were larger than in the right. CONCLUSION: The lingual function of cerebellum is not only limited in the right,the left cerebellar,hemisphere may be engaged the processing of lingual function.