CAJ | 학술논문

目的研究北京城乡结合部与市区自然人群亚临床颈动脉硬化特征,为实施心血管疾病风险监测与健康管理提供依据.方法参照ARIC方案,从2002年10月至2007年9月对北京市2101例自然人群(分为市区组899例和城乡组1202例两组)进行高分辨率B超颈动脉检查,测量双侧颈总动脉近端、远端和窦部的内中膜厚度(IMT)、颈总动脉斑块,颈总动脉内径并计算动脉紧张度,比较两种不同区域人群上述指标分布特征.结果两组人群颈总动脉IMT随着年龄增长而增加(男性均P<0.05,女性均P<0.05),男女各年龄段城乡结合部人群IMT明显厚于市区人群(均P<0.05).无论男女,两组人群颈动脉斑块检出率随着年龄增长而增加(男性均P<0.05,女性均P<0.05),城乡结合部人群斑块检出率明显高于市区人群(均P<0.05).两组人群颈动脉紧张度随年龄增加呈现减低趋势(均JP<0.05),城乡结合部人群减低趋势更加明显(P<0.05).结论随着我国城市化和老龄化进程加快,心血管疾病风险监测与健康管理的重点人群应放在城乡结合部人群和中老年人群.
목적 연구북경성향결합부여시구자연인군아림상경동맥경화특정,위실시심혈관질병풍험감측여건강관리제공의거.방법 삼조ARIC방안,종2002년10월지2007년9월대북경시2101례자연인군(분위시구조899례화성향조1202례량조)진행고분변솔B초경동맥검사,측량쌍측경총동맥근단、원단화두부적내중막후도(IMT)、경총동맥반괴,경총동맥내경병계산동맥긴장도,비교량충불동구역인군상술지표분포특정.결과 량조인군경총동맥IMT수착년령증장이증가(남성균P<0.05,녀성균P<0.05),남녀각년령단성향결합부인군IMT명현후우시구인군(균P<0.05).무론남녀,량조인군경동맥반괴검출솔수착년령증장이증가(남성균P<0.05,녀성균P<0.05),성향결합부인군반괴검출솔명현고우시구인군(균P<0.05).량조인군경동맥긴장도수년령증가정현감저추세(균JP<0.05),성향결합부인군감저추세경가명현(P<0.05).결론 수착아국성시화화노령화진정가쾌,심혈관질병풍험감측여건강관리적중점인군응방재성향결합부인군화중노년인군.
Objective To describe the characteristics of subclinical carotid atherosclerosis in urban or suburban populations to provide support for cardiovascular risk factors monitoring and health management.Methods A population-based cardiovascular epidemiology survey was conducted among 899 urban and 1202 suburban residents in Beijing from October 2002 to September 2007.Carotid plaque.intimamedia thickness(IMT),and lumen diameter were measured in the proximal,distal,and sinus segment of the carotid artery using duplex ultrasound.Arterial tension and the number of plaques were calculated and compared between the two groups.Results Mean common carotid IMT increased with age in both groups (P<0.05,respectively),and among all age groups IMT Was obviously thicker in suburban population than that in urban population (respectively,P<0.05).Independence of gender,the prevalence of plaques increased with age (P<0.05),and the number of plaques was higher in the suburban population than those in urban population in all age groups (P<0.05).However,aaerial tension decreased with age in both groups,especially in the suburban populations (P<0.05).Conclusion With the acceleration of urbanization and aging in China,cardiovascular risk factor monitoring and health management should focus on suburban and elderly populations.