CAJ | 학술논문

目的探讨血清降钙素原(PCT)检测对重症急性胰腺炎(SAP)并发感染的诊断价值.方法 65例SAP患者中合并细菌感染47例(合并感染组)和非感染患者18例(非感染组),采用双抗夹心免疫发光法测定两组患者血清PCT水平,采用电泳法测定C-反应蛋白(CRP)水平,同时检测两组外周血白细胞计数(WBC)、体温(T)及急性生理和慢性健康标准评分(APACHE-Ⅱ)等.结果 SAP合并感染组PCT水平(4.58±1.20)μg/L,明显高于非感染组的(1.72±0.53)μg/L(t=3.01,P＜0.05);两组CRP、WBC、T和A-PACHE-Ⅱ评分等差异均无统计学意义(均P＞0.05).结论血清PCT水平显著增高可能与SAP患者并发感染有关,是SAP并发感染的一个较好的诊断和观察指标.
목적 탐토혈청강개소원(PCT)검측대중증급성이선염(SAP)병발감염적진단개치.방법 65례SAP환자중합병세균감염47례(합병감염조)화비감염환자18례(비감염조),채용쌍항협심면역발광법측정량조환자혈청PCT수평,채용전영법측정C-반응단백(CRP)수평,동시검측량조외주혈백세포계수(WBC)、체온(T)급급성생리화만성건강표준평분(APACHE-Ⅱ)등.결과 SAP합병감염조PCT수평(4.58±1.20)μg/L,명현고우비감염조적(1.72±0.53)μg/L(t=3.01,P＜0.05);량조CRP、WBC、T화A-PACHE-Ⅱ평분등차이균무통계학의의(균P＞0.05).결론 혈청PCT수평현저증고가능여SAP환자병발감염유관,시SAP병발감염적일개교호적진단화관찰지표.
Objective To investigate the value of serum procalcitonin(PCT)level in diagnosis of severe acute pancreatitis(SAP)complicated with infection.Methods 65 cases of SAP who were treated as research subjects and divided into infection group with 47 cases and non-infected group with 1 8 cases according to whether complicated with infection or not.The serum PCT,C-reactive protein(CRP),white blood cell count(WBC),temperature(T)and acute physiology and chronic health standards score(APACHE-Ⅱ)of the two groups were compared and analyzed.Results The serum PCT level of SAP co-infection group was(4.58±1.20)μg/L which was significandy higher than non-infected group,the difference between groups was statistically significant(P＜0.05);but the CRP,WBC,T and APACHEⅡscore compared with non-infected group had no significant difference(P＞0.05).Conchrsion The significant increase of serum PCT level in patients with SAP maybe relate to whether complicated with infection or not.and it was a better diagnosis and observation index for SAP complicated with infection and had important clinical significance.