CAJ | 학술논문

通过犬自体肾移植模型研究了一定浓度的川芎嗪加入WMO-1号液对犬肾保存效果的影响.结果表明,单纯WMO-1号液保存72小时和加川芎嗪保存72小时的肾行自体移植均难存活;加川芎嗪保存48小时组术后血肌酐的平均值低于单纯WMO-1号液保存48小时组,且血肌酐恢复正常的时间也较单纯WMO-1号液组早(P＜0.05),说明该实验浓度的川芎嗪不能延长肾保存时间,但有利于移植肾功能的早期恢复.
통과견자체신이식모형연구료일정농도적천궁진가입WMO-1호액대견신보존효과적영향.결과표명,단순WMO-1호액보존72소시화가천궁진보존72소시적신행자체이식균난존활;가천궁진보존48소시조술후혈기항적평균치저우단순WMO-1호액보존48소시조,차혈기항회복정상적시간야교단순WMO-1호액조조(P＜0.05),설명해실험농도적천궁진불능연장신보존시간,단유리우이식신공능적조기회복.
The canine kidney autologous transplant model was used to investigate the effect of ligustrazine with a certain concentration added to WMO-1 solution on kidney preservation. The results showed that the canine autologously transplanted kidneys were difficult to survive with 72h preservation of WMO-1 alone and WMO-1 plus ligustrazine. The mean serum creatine level after operation in 48 h ligustrazine preservation group was lower than in 48 h WMO-1 preservation group, and the recovery of serum creatine level in the former group was earlier than in the latter group (P＜0.05). These results suggested that the ligustrazine concentration used could not prolong the preservation time of WMO-1 solution to kidney, but could be of benefit to the recovery of renal function in the early stage.