CAJ | 학술논문

目的探讨高龄双胎妊娠的围产结局.方法回顾性分析我院69例高龄双胎病例,随机对照176例非高龄双胎的临床资料,比较两组在妊娠并发症、妊娠合并症、和胎儿预后等方面的差异.结果 ①高龄组接受辅助生育技术受孕比例显著高于非高龄对照组(P＜0.05);②高龄组＜32孕周早产发生率明显高于对照组(P＜0.05),而其他并发症及合并症两组间未见显著性差异;③高龄组以极低出生体重儿(＜1500 g)比例显著高于对照组(P＜0.05).高龄组新生儿窒息率及胎儿窘迫发生率明显增高(P＜0.05).结论高龄双胎妊娠不良妊娠结局主要与＜32孕周的严重早产、极低体重儿、新生儿窒息及胎儿窘迫密切相关,应针对性加强高龄双胎的围生期监护,警惕严重早产的发生.
목적 탐토고령쌍태임신적위산결국.방법 회고성분석아원69례고령쌍태병례,수궤대조176례비고령쌍태적림상자료,비교량조재임신병발증、임신합병증、화태인예후등방면적차이.결과 ①고령조접수보조생육기술수잉비례현저고우비고령대조조(P＜0.05);②고령조＜32잉주조산발생솔명현고우대조조(P＜0.05),이기타병발증급합병증량조간미견현저성차이;③고령조이겁저출생체중인(＜1500 g)비례현저고우대조조(P＜0.05).고령조신생인질식솔급태인군박발생솔명현증고(P＜0.05).결론 고령쌍태임신불량임신결국주요여＜32잉주적엄중조산、겁저체중인、신생인질식급태인군박밀절상관,응침대성가강고령쌍태적위생기감호,경척엄중조산적발생.
Objective The aim of this study is to present perinataloutcomes of twin gestations in older women. Methods We conducted a retrospective cohort study of 69 cases of twin pregnancies maternal age 35 years and older( study group)in our department, compared with 176 twin pregnancies cases of maternal age less than 35 years( control group). Results ①Conceptions after assisted reproductive technology were significantly higher in study group(P＜0.05 ). ②The rate of preterm labour lower than 32 gestational weeks was significantly higher in the study group(P＜0.05). The other complications rate did not differ singnificantly from the control groups. (3) The very low birth weight ( VLBW ＜ 1,500 g) rate was significantly higher in the study group ( P＜0.05 ), the rate of neonatal asphyxia and fetal distress were statistically significant higher in study group (P＜0.05). Conclusion Advanced maternal age was related with higher incidence of the severe preterm labour(＜32 gestational weeks) ,the very low birth weight(＜1,500 g) ,fetal distress,neonatal asphyxia. It is important to close monitoring during perinatal period in women aged 35 and over with twin pregnancy, watch out for the severe preterm labour.