中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
3期
23-24
,共2页
匹维溴胺%盐酸帕罗西丁片%抑郁%肠易激综合征
匹維溴胺%鹽痠帕囉西丁片%抑鬱%腸易激綜閤徵
필유추알%염산파라서정편%억욱%장역격종합정
Pinaverium bromide%Paroxetine Hydrochloride Tablets%Despondent%Irritable bowel syndrome
目的 观察匹维溴胺联合盐酸帕罗西丁片(赛乐特)对伴有抑郁状态的肠易激综合征患者的治疗效果.方法 按罗马Ⅱ标准选择伴抑郁状态的IBS患者,分为两组,单用匹维溴胺治疗者为对照组,联合应用匹维溴胺及盐酸帕罗西丁片者为治疗组、对照组口服匹维溴胺50 mg,tid;治疗组在匹维溴胺基础上加用盐酸帕罗西丁片,每日1片.对患者腹痛、腹胀、腹泻、便秘、粘液便、里急后重、排便不尽感及抑郁状态进行评分,比较治疗前后评分结果.结果 治疗2周及4周后,治疗组和对照组的症状学评分及SDS评分均有所降低,但治疗组各症状学评分及SDS评分较对照组有明显差异(P＜0.05).结论 匹维溴胺联合盐酸帕罗西丁片应用能有效治疗伴抑郁状态的肠易激综合症.
目的 觀察匹維溴胺聯閤鹽痠帕囉西丁片(賽樂特)對伴有抑鬱狀態的腸易激綜閤徵患者的治療效果.方法 按囉馬Ⅱ標準選擇伴抑鬱狀態的IBS患者,分為兩組,單用匹維溴胺治療者為對照組,聯閤應用匹維溴胺及鹽痠帕囉西丁片者為治療組、對照組口服匹維溴胺50 mg,tid;治療組在匹維溴胺基礎上加用鹽痠帕囉西丁片,每日1片.對患者腹痛、腹脹、腹瀉、便祕、粘液便、裏急後重、排便不儘感及抑鬱狀態進行評分,比較治療前後評分結果.結果 治療2週及4週後,治療組和對照組的癥狀學評分及SDS評分均有所降低,但治療組各癥狀學評分及SDS評分較對照組有明顯差異(P＜0.05).結論 匹維溴胺聯閤鹽痠帕囉西丁片應用能有效治療伴抑鬱狀態的腸易激綜閤癥.
목적 관찰필유추알연합염산파라서정편(새악특)대반유억욱상태적장역격종합정환자적치료효과.방법 안라마Ⅱ표준선택반억욱상태적IBS환자,분위량조,단용필유추알치료자위대조조,연합응용필유추알급염산파라서정편자위치료조、대조조구복필유추알50 mg,tid;치료조재필유추알기출상가용염산파라서정편,매일1편.대환자복통、복창、복사、편비、점액편、리급후중、배편불진감급억욱상태진행평분,비교치료전후평분결과.결과 치료2주급4주후,치료조화대조조적증상학평분급SDS평분균유소강저,단치료조각증상학평분급SDS평분교대조조유명현차이(P＜0.05).결론 필유추알연합염산파라서정편응용능유효치료반억욱상태적장역격종합증.
Objective To study the therapeutic effects of pinaverium bromide combined with Paroxetine? Hydrochloride Tablets in treatmentment of irritable bowel syndrome(IBS)with despondent. Methods 120patients of IBS with despondent were divided into two groups, One group treated with pinaverium bromide 50 mg tid named Comparison group;the other group treated with pinaverium bromide 50 mg tid combined with Paroxetine? Hydrochloride Tablets 1 sheet per day named treatment group. Results After 2 weeks、4 weeks of treatment, the semiology scores were all decreased in two groups. But in treatment group,the therapeutic effects of all symptom and SDS grading Were significantly higher than Comparison group( P ＜ 0.05 ). Conclusion Pinaverium bromide combined with Paroxetine Hydrochloride Tablets can effectively allevite symptoms of IBS with despondent.
